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Diet and oral health: a study on gum inflammation

Dietary and Inflammatory Profile in Periodontal Health, Gingivitis, and Periodontitis: A Cross-Sectional Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-348dzv9
Enrollment
72
Registered
2026-05-25
Start date
2026-05-04
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

This is a cross-sectional observational study. A total of 72 individuals who meet the eligibility criteria will be divided into three groups according to periodontal condition: Periodontal Health grou

Sponsors

Universidade de São Paulo
Lead Sponsor
Faculdade de Odontologia de Ribeirão Preto da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Systemically healthy individuals of both sexes, aged 18 years or older, presenting at least 15 natural teeth, excluding third molars and teeth indicated for extraction; participants will be allocated into the Periodontal Health, Gingivitis, and Stage III Periodontitis, grade B or C groups according to the periodontal classification; Periodontal Health group: absence of clinical attachment loss and bone loss due to periodontitis, probing depth less than or equal to 3 mm at all sites, and bleeding on probing less than or equal to 10%; Gingivitis group: more than 30% of sites with bleeding on probing, probing depth less than or equal to 3 mm, and absence of clinical attachment loss and bone loss due to periodontitis; Stage III Periodontitis, grade B or C group: at least 30% of teeth presenting at least 1 site with probing depth and clinical attachment level greater than or equal to 5 mm, associated with bleeding on probing

Exclusion criteria

Exclusion criteria: Use of antibiotics, probiotics and/or prebiotics within the last 6 months; periodontal treatment performed within the last 6 months; continuous use of mouthwashes containing antimicrobial agents; prolonged use of anti-inflammatory or immunosuppressive medications; presence of systemic conditions that may interfere with the progression of periodontal diseases, such as diabetes, obesity, or immunological disorders; presence of chronic gastrointestinal diseases; individuals with extensive prosthetic rehabilitations; need for antibiotic prophylaxis for routine dental procedures; smokers; pregnant or breastfeeding women

Design outcomes

Primary

MeasureTime frame
Assessment of the Dietary Inflammation Index (DII) in individuals with healthy gums, gingivitis, and stage III periodontitis (grades B or C).

Secondary

MeasureTime frame
Association between IID and periodontal clinical parameters.

Countries

BR

Contacts

Public ContactFlávia Aparecida Furlaneto

Universidade de São Paulo

flafurlaneto@hotmail.com+55 (16) 3602-4140

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Jun 11, 2026