Appetite
Conditions
Interventions
Treatment A: standard breakfast (180mL of milk 3% fat, 60mL of infusion coffee 5%, 10g of crystal sugar, 50g of french bread, 15g of butter, 32g of cheese, 100mL of water) and yacon syrup (40g of malt
Dietary supplement
Sponsors
Fundação Universidade Estadual do Ceará FUNECE
Empresa Brasileira de Pesquisa Agropecuária
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women; between 20 and 40 years old; do not present chronic self-reported diseases; have a body mass index of eutrophy or obesity grade I; regular menstrual cycle.
Exclusion criteria
Exclusion criteria: Pregnancy or lactation; hysterectomy performed; current smoker or in the last 30 days; users of illicit drugs; daily consumption of ethanol higher than 15g; current or last 30 days use of hypoglycemic, lipid-lowering, antibiotic and anti-inflammatory medications, laxatives or weight-loss medications; have inflammatory diseases such as inflammatory bowel disease (Crohn's disease, ulcerative colitis); endocrinopathy carrier’s (cushing's syndrome, hypothyroidism), cancer carrier’s, having celiac disease or lactose intolerance; have constipation history; present current consumption and in the last 30 days of fiber and fructooligosaccharides supplementation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the postprandial response of the plasma biomarkers of appetite after ingestion of yacon syrup compared to placebo;verified by blood dosage of glucagon-like peptide 1 (GLP1) and ghrelin at times 0, 15, 30, 45, 60, 90, 120 and 180. The improvement will be verified if there is statistical significance (p <0.05) in the comparison of the areas under the curve between treatment A (syrup intake) and treatment B (placebo intake), a difference of at least 50% between treatments is expected. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of the postprandial response of serum glycemia, serum insulin, serum triglycerides and subjective sensation of satiety after yacon syrup ingestion compared to placebo; verified by glucose, insulin and triglycerides blood dosages and self-reporting on satiety at times 0, 15, 30, 45, 60, 90, 120 and 180. The improvement will be verified if there is statistical significance (p <0, 05) in the comparison of the areas under the curve between treatment A (syrup intake) and treatment B (placebo intake), a difference of at least 50% between treatments is expected. | — |
Countries
Brazil
Contacts
Public ContactLia Adriano
Fundação Universidade Estadual do Ceará FUNECE
Outcome results
None listed