people living with HIV/aids
Conditions
Interventions
Interventions to experimental group: Use of propolis-containing tablets (20 patients). Interventions to placebo group: Use of tablets without the active substance (20 patients). The 40 participants wi
Other
E01.370.225.998.110
Sponsors
Instituto de Biociências de Botucatu - UNESP
Faculdade de Medicina de Botucatu
Eligibility
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: To have confirmed HIV infection and use of cART with adequate viral suppression for at least three years; have a minimum age of 20 and a maximum of 50, and sign a Consent Form.
Exclusion criteria
Exclusion criteria: cART patients for more than 10 years and / or under rescue therapy; vertical transmission; patients with cancer, diabetes mellitus, cardiovascular or autoimmune diseases; transplanted; patients who exercise regularly; pregnant or lactating women; presence of co-infections such as tuberculosis, viral hepatitis, toxoplasmosis, among others; genetic diseases; treatment with anxiolytics or antidepressants; vitamin supplementation; users of illicit drugs, active smokers and alcoholics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-inflammatory and anti-oxidant activity determined by the analysis of immunological markers at the beginning and at the end of the study | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease inflammatory status, immune activation, microbial translocation, increase levels of CD4 + T and balance the profile of T helper responses, as well as cytokines. | — |
Countries
Brazil
Contacts
Public ContactKaren Tasca
Instituto de Biociências de Botucatu - UNESP
Outcome results
None listed