Healthy humans undergoing orthodontic treatment will be screened for assesment of bisphenol-A in saliva Specific descriptors: Bis-Phenol A-Glycidyl Methacrylate
Conditions
Interventions
In vitro analysis of a bisphenol A free resin restorative system by gas chromatography to verify the absence of the compound studied with samples of 4 specimens for each system - Transbond XT, Orthoc
Mechanical shear bond and micro-shear bond tests in the resin restorative system free of bisphenol A (Resin Vittra FGM - conventional and modified technique) and in the control group (Transbond XT) to
To perform in vivo analysis by collecting saliva samples
(5 times - baseline, 30 minutes after orthodontic bonding, 24 hours, 7 days and 30 days) from patients who will receive orthodontic appliances
Procedure/surgery
E06.658.453.590
D003764
D003188
Sponsors
Faculdade de Odontologia de Ribeirão Preto
Faculdade de Odontologia de Ribeirão Preto
Eligibility
Age
12 Years to 20 Years
Inclusion criteria
Inclusion criteria: Age between 12 and 20 years; without gender preference; with complete permanent dentition; without lesions of caries and or periodontal disease; nonsmokers who will start treatment with fixed orthodontic appliances at the Orthodontics Specialization Clinic of the School of Dentistry of Ribeirão Preto USP; Patients should be good general health; have not received restorations in composite resins and or sealants in the last three months and do not engage in occupations that may be linked to BPA exposure.
Exclusion criteria
Exclusion criteria: Patients who are not in the criteria described in the inclusion; Patients who have received restorations in composite resins and or sealants in the last three months; and patients who have occupations related to BPA exposure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is estimated with this research that the test materials (Ambar APS adhesive and VIttra APS resin) are actually BPA free according to chromatographic chemical evaluation;It is estimated with this research that the test materials (Ambar APS adhesive and VIttra APS resin) they present good mechanical resistance compatible with orthodontic forces after undergoing shear and micro-shear bond tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is estimated that the test materials presents good mechanical resistance compatible with clinical orthodontic forces (5 a 8 MPa);It is estimated that the test materials do not alter salivary levels of Bisphenol-A in patients who have orthodontic appliances fixed with the test material, condition assessed by gas chromatography and analysis of orthodontic bracket survival and adhesive remnant index. | — |
Countries
Brazil
Contacts
Public ContactRenata Zoraida Delgado
Faculdade de Odontologia de Ribeirão Preto
Outcome results
None listed