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Effects of Cardiac Rehabilitation on Exercise Tolerance, Endothelial Function, Heart Variability and Quality of Life in Heart Transplants.

Effects of Cardiac Rehabilitation on Functional Capacity, Endothelial Function, Cardiac Variability and Quality of Life in Heart Transplant recipients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-32vrj6
Enrollment
Unknown
Registered
2018-05-11
Start date
2018-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Transplantation

Interventions

All participants in the study will be individuals who have already undergone heart transplantation. Individuals will be allocated into two groups, the control group (1) and the experimental group (2).
Other
E02.760.169.063.500.185

Sponsors

Universidade Federal de Pernambuco-UFPE
Lead Sponsor
Universidade Federal de Pernambuco-UFPE
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Individuals with an age range greater than 18 years and less than 65 years of age; of both sexes; who underwent heart transplant surgery in a superior period for 6 months; with clinical stability; using regular immunosuppressive therapy, with no change in class of medications within three months prior to the start of the study

Exclusion criteria

Exclusion criteria: Patients who present with orthopedic, neurological or respiratory diseases that may make it impossible to perform cardiopulmonary and exercise tests; patients who are undergoing dialysis; and those patients who present psychic alterations that restrict them to respond to the questionnaires and the elderly who carry out the test Time up and go in time greater than 20 seconds, characterizing risk of falls

Design outcomes

Primary

MeasureTime frame
Expected outcome 1 Maximum oxygen consumption (VO2max) as measured by Ergospirometry.;Expected outcome 2 Heart rate variability through time domain analysis parameters: mean RR, SDNN, SDNNi, SDANN, rMSSD and PNN50, and frequency domain analysis: AF, BF and BF / AF measured by Holter. ;Expected outcome 3 Endothelial function through the RHI (Reactive hyperemia index analyzed by EndoPAT 2000.;Expected outcome 4 Quality of life measured through the Short Form-36 questionnaire (SF-36).—

Secondary

MeasureTime frame
Expected outcome 1 Distance traveled in meters obtained in the Six-Minute Walk Test (TC6) ;Expected outcome 2 Symptoms of depression through the Beck Depression Inventory (BDI);Expected outcome 3 Inspiratory muscle strength measured by the Digital Manovacuometer (GlobalMed)—

Countries

Brazil

Contacts

Public ContactJuliana Ferreira de Souza

Universidade Federal de Pernambuco-UFPE

juafsouza@yahoo.com.br+55-081-991891084

Outcome results

None listed

Source: REBEC (via WHO ICTRP)