Attention-deficit hyperactivity disorder, predominantly inattentive type
Conditions
Interventions
A two-arm, double-blind, parallel-group study, with the primary outcome being the improvement in working memory task performance after four sessions of high-definition transcranial alternating current
E02.331.750
Sponsors
Campus Integrado de Manufatura e Tecnologia - CIMATEC / SENAI
Campus Integrado de Manufatura e Tecnologia - CIMATEC / SENAI
Eligibility
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: Provision of Free and Informed Consent in writing, signed and dated; provision of the assent term in writing, signed and dated; individuals of both sexes; right-handed; aged 12-18 years; diagnosed with Attention Deficit Hiperativity Deficit (ADHD) according to DSM-V criteria; residing in Salvador and the metropolitan area; enrolled in regular school or who have already completed high school; and who have medical authorization to suspend the use of psycho-stimulant medication for 48 hours prior to the interventions and for an additional 5 days during the intervention period. Individuals of both sexes; aged 12-18 years; without a diagnosis of ADHD; residing in Salvador and the metropolitan area, enrolled in regular school or who have already completed high school.
Exclusion criteria
Exclusion criteria: Research participants who have been involved in clinical study protocols in the last 12 (twelve) months, unless the investigator deems there may be a direct benefit to them (CNS Resolution 251, dated August 7, 1997, item III, subitem J); alcohol and drug abuse (previous diagnosis according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders – DSM-V); use of illegal drug; any clinical condition interpreted by the investigating physician as a risk for the participant’s inclusion in the study, presence of head injuries contraindicating the use of neuromodulation; use of pacemakers; cochlear implants, or metal plates in the head; brain tumors; cranial deformities; diagnosis of depression and/or anxiety disorders, according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), in the last 6 months; diagnosis of bipolar disorder, schizophrenia, autism spectrum disorder, and other developmental disorders diagnosed according to DSM-V; diagnosis of epilepsy; pregnant individuals; diagnosis of ADHD only with hyperactive presentation; initiation of new psychotropic medications or changes in the dosage of usual medication in the last 3 months; ose of psycho-stimulants 48 hours before and during the intervention; Oral language disorders and cognitive disorders that hinder understanding of the study procedures and the necessary responses; individuals who have suffered acquired neurological disorders or have congenital neurological disorders that may interfere with understanding the study results: cerebrovascular accidents, encephalopathies; visual or auditory impairments that prevent effective use of Virtual Reality; Episodes of nausea and labyrinthitis that, even when treated, hinder the use of Virtual Reality; any condition that, in the opinion of the principal investigator, poses a risk to the research participant during their participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvements in the working memory task are expected after 4 sessions of high or low-frequency high-definition transcranial alternating current stimulation in the left dorsolateral prefrontal cortex or inferior parietal lobe in patients with ADHD | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvements in inhibitory control (impulsivity) during a working memory task are expected in adolescents with ADHD in the short term (immediate) and medium term (30 days). | — |
Countries
Brazil, Spain
Contacts
Public ContactCamila Guimarães
Serviço Nacional de Aprendizagem Industrial
Outcome results
None listed