Essential Hypertension
Conditions
Interventions
This is a two-arm Randomized Clinical Trial (RCT). A random sequence will be generated by computer software (http://www.random.org/), which will be followed to allocate participants into groups with a
VS3.003.001.006.005
Sponsors
Hospital da Mulher Professor Doutor José Aristodemo Pinotti - Centro de Atenção Integral à Saúde da Mulher
Universidade Estadual de Campinas
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All pregnant women diagnosed with chronic hypertension and clinical suspicion of superimposed preeclampsia (due to worsening blood pressure control); age over 18 years; gestacional age over 20 weeks; exacerbated weight gain; emergence or worsening of proteinuria; signs of placental insufficiency after 20 weeks of gestation
Exclusion criteria
Exclusion criteria: HELLP syndrome; eclampsia; signs of imminent eclampsia; hypertensive crisis, when systolic blood pressure =160 and/or diastolic blood pressure =110mmHg; acute fetal distress
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduce frequency of prematurity related to superimposed pre-eclampsia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Implementing the use of PlGF will reduce the need for hospitalization and costs in chronic hypertension cases.;Implementing the use of PlGF will reduce the frequency of cesarean births and severe pré-eclâmpsia.;Implementing the use of PlGF will improve the perinatal outcome of superimposed preeclampsia cases.;The groups will be similar in sociodemographic characteristics and background. | — |
Countries
Brazil
Contacts
Public ContactMaria Laura Costa do Nascimento
Universidade Estadual de Campinas
Outcome results
None listed