Cystic Fibrosis
Conditions
Interventions
The sample will be composed of 46 children and adolescents between 6 and 15 years of age, clinically stable, with a diagnosis of Cystic Fibrosis (CF) confirmed in accordance with the Brazilian Guideli
b) genetic mutation (presence or absence of at least one DeltaF508 allele)
c) spirometric parameters (forced expiratory volume in the first second and forced expiratory flow from 25% to 75% of forced vital capacity, in absolute values ??and percentage of predicted)
d) Schwachman-Doershuk score (applied by the medical team at the reference center and categorized as excellent / good and medium / moderate). Then, the team of researchers will apply 2 acute pulmonary
Other
Sponsors
Universidade do Estado de Santa Catarina - UDESC
Universidade do Estado de Santa Catarina - UDESC
Hospital Infantil Joana de Gusmão
Eligibility
Age
6 Years to 15 Years
Inclusion criteria
Inclusion criteria: Children and adolescents between 6 and 15 years old, with confirmed CF diagnosis, and being followed up at the HIJG reference center, clinically stable, who are not hospitalized or with indication for admission at the time of data collection will be included in the research. To participate in the study, parents or guardians must present the free and informed consent form (ICF) and the child or adolescent must consent to participate, by signing the free and informed consent form.
Exclusion criteria
Exclusion criteria: Individuals who demonstrate an inability to properly perform any of the proposed assessment procedures will be excluded, thus preventing the continuity of data collection. Individuals whose data appears to be doubtful will also be excluded from the sample.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immediate effect of TEF on respiratory mechanics parameters in children and adolescents with CF. It will be performed in the pre-FET, post-huff and post-FET moments using the impulse oscillometry (IOS) system presented in kilopascals-kPa and in percentages of the predicted. | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters of respiratory mechanics in patients with CF presented episodes of coughing during the protocol and those that did not. Anthropometric data of mass in kilogram-kg and height in meters-m and BMI in kg / m2). Score of clinical scores for clinical stability (CFCS and CFFS). | — |
Countries
Brazil
Contacts
Public ContactPatricia Rentz Keil
Universidade do Estado de Santa Catarina - UDESC
Outcome results
None listed