Other primary knee osteoarthritis
Conditions
Interventions
The present study is a prospective and randomized clinical trial with the objective of evaluating the effects of using platelet-rich plasma in comparison with hyaluronic acid for the conservative trea
Sponsors
Faculdade de Medicina da Universidade Federal Fluminense
Hospital Universitário Antonio Pedro/Empresa Brasileira de Serviços Hospitalares
Eligibility
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age between 40 and 70 years old; both sexes; diagnosis of Bilateral Osteoarthritis of the knee, according to the criteria of the American College of Rheumatology; radiographs with a Kellgren-Lawrence classification of less than III in both knees; present full range of motion (0 to 120°)
Exclusion criteria
Exclusion criteria: History of previous trauma, infection or surgery in the same knee in the last 2 years;limb malalignment (varus>10º and valgus > 15º);corticosteroid infiltration in the same knee in the last 3 months;hyaluronic acid ; unfiltration in the same knee in the last 12 months;inflammatory, autoimmune or neoplasic disease;body mass index> 35 kg/m2; use of immunosuppressants or anticoagulants; active neoplasia; hematologic disorders; history of transmissible disease accute or chronic; living outside Rio de Janeiro metropolitan area; participants without full autonomy, blind, deaf or illiterate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain analysed by visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Function analysed by WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) and KSS (Knee Society Score) | — |
Countries
Brazil
Contacts
Public ContactEduardo de Sousa
Universidade Federal Fluminense
Outcome results
None listed