Chronic kidney disease
Conditions
Interventions
Patients will be randomized to undergo to 12 consecutive dialysis sessions in each arm:
A) Hemodialysis using 4.0 mEq/L acetate buffer dialisate and heparin dose 100 IU/Kg.
B) Hemodialysis using 2.4 m
other
D26.776.708.322.651
Sponsors
Divisão de Nefrologia da Faculdade de Medicina da Universidade Federal Fluminense
CDR- Clínica de Doenças Renais
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients older than 18 years of age, both genders, on maintenance hemodialysis, without major comorbidities.
Exclusion criteria
Exclusion criteria: Prescription of hemodialysis shorter than 3h 30 min. Use of oral anticoagulant. Use of temporary double lumen catheter. Awating for living donor kidney transplant. Refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Loss of the dialyzer before 12th use due to clotting of blood in the extracorporeal circuit or reduction of fiber bundle volume >20% of baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of hemodialysis efficiency assessed by the urea Kt/V at 1st, 6th and 12th dialysis sessions of each phase. Incidence of hypocalcemia or hypomagnesemia in each phase of the study. | — |
Countries
Brazil
Contacts
Public ContactAmanda;Amanda Rocha;Rocha
Divisão de Nefrologia da Faculdade de Medicina da Universidade Federal Fluminense;Divisão de Nefrologia da Faculdade de Medicina da Universidade Federal Fluminense
Outcome results
None listed