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Use of laser in the treatment of injuries caused by Radiotherapy

Prevention of Oral mucositis induced by Radiotherapy of head and neck: effect of the combination of red and infrared lasers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2ybrb4d
Enrollment
Unknown
Registered
2021-02-09
Start date
2015-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral mucositis

Interventions

The patients were randomized by lot and divided into 3 groups, according to the sequence of treatments to be performed, being: Red laser (Group 1) - 26 subjects
Infrared laser (Group 2) - 25 subjects
and associated infrared and red lasers (Group 3) - 29 subjects. There was no control group. All patients received, at 30 points with a higher prevalence of OM, the application of low intensity laser t
C07.465.864

Sponsors

Universidade de Passo Fundo
Lead Sponsor
Associação Hospitalar Beneficente São Vicente de Paulo
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Be over 18 years old; having an indication for outpatient radiotherapy treatment for head and neck cancer with or without adjuvant chemotherapy; present physical and psychological conditions to receive the treatments proposed in the methodology of this research; having signed the free and informed consent form.s

Exclusion criteria

Exclusion criteria: Patients undergoing clinical complications that prevent the study, such as interruption of radiotherapy for more than a week or limited mobility, will be excluded from the research; patients who refuse to apply the therapy within the proposed treatment logistics or who do not adhere to the requested oral hygiene protocol.s

Design outcomes

Primary

MeasureTime frame
Oral mucositis (MO); three times a week, the degree of OM was measured by the WHO scale, until its complete remission; The results indicate a significant difference in the OM score between the three groups, with Group 3 (660 nm + 810 nm) presenting lower OM scores (p = 0.012) than Group 1 (660 nm) and Group 2 ( 810 nm).;Pain; it was measured daily using the Visual Analogue Scale (EVA); There was no significant difference in pain scores (VAS) between groups (p = 0.49).

Secondary

MeasureTime frame
They were not expected and no secondary outcomes were found.

Countries

Brazil

Contacts

Public ContactJoão De Carli
joaodecarli@upf.br55 (54) 99112-3079

Outcome results

None listed

Source: REBEC (via WHO ICTRP)