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The effect of Chlorhexidine mouth rinses on blood pressure in healthy people

Evaluation of the effect of Chlorhexidine mouthwash use on blood pressure in healthy individuals

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2y72dnm
Enrollment
Unknown
Registered
2025-09-29
Start date
2024-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arterial pressure

Interventions

This is a randomized, double-blind, crossover, intra-subject clinical trial with a sample of 26 healthy individuals. Participants will be randomly assigned to receive a bottle of mouthwash without ide
D25.583
D02.078.370.141.100

Sponsors

Centro Universitário do Planalto Central - Uniceplac
Lead Sponsor
Centro Universitário do Planalto Central - Uniceplac
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years; good health status

Exclusion criteria

Exclusion criteria: Use of antimicrobials and/or mouthwash in the past three months; Smoking; Alcoholism; Diabetes; Autoimmune diseases; Gingivitis; Periodontitis; Oral mucosal lesions; Borderline blood pressure values

Design outcomes

Primary

MeasureTime frame
Expected outcome 1 Based on previous studies, an average increase of 5 mmHg in systolic and diastolic blood pressure is expected after 7 days of using chlorhexidine mouthwash, as assessed by standardized measurements taken before and after the intervention.—

Secondary

MeasureTime frame
No secondary outcomes are expected—

Countries

Brazil

Contacts

Public ContactAdriana Cruz

Centro Universitário do Planalto Central - Uniceplac

adriana.cruz@uniceplac.edu.br+55(61)30353900

Outcome results

None listed

Source: REBEC (via WHO ICTRP)