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Effects of low oxygen intervals during exercise on human body function

Effects of intermittent hypoxia recovery on molecular, metabolic and neuromuscular variables

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2xq4vw4
Enrollment
Unknown
Registered
2024-08-27
Start date
2022-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physical Functional Performance

Interventions

This is a randomized controlled clinical study involving a total of seventy healthy men. Three experiments will be conducted, with Experiment One including twenty participants, Experiment Two includin
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Sponsors

Universidade de São Paulo
Lead Sponsor
Escola de Educação Física e Esporte de Ribeirão Preto da Universidade de São Paulo
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Man; healthy; aged 18 to 35 years old

Exclusion criteria

Exclusion criteria: History of anemia in the last six months; history of lower limb injury in the last six months; and presented low ferritin levels at the beginning of the experiment

Design outcomes

Primary

MeasureTime frame
It is expected that hypoxia during recovery will improve performance more than the other conditions

Secondary

MeasureTime frame
Establishing the temporal course of physiological responses and gene expression associated with muscular adaptations from various hypoxia exposure models combined with a HIIT model;Quantifying metabolic involvement and modulating fatigue arising from hypoxia exposure, focusing on the shift from aerobic to anaerobic metabolism and mitigating central and peripheral fatigue effects;Developing an optimized monitoring model for hypoxia training to enhance muscular reoxygenation and anaerobic participation while maintaining training quality;Find chronic benefits of different training models combined with hypoxia exposure, potentially benefiting both sports performance and health by exploring applications in conditions such as obesity, cardiovascular diseases, diabetes, and neurodegenerative disorders

Countries

Brazil

Contacts

Public ContactMatheus Norberto

Universidade de São Paulo

matheus.norberto@usp.br+55 (019) 999557080

Outcome results

None listed

Source: REBEC (via WHO ICTRP)