Muscle spasticity
Conditions
Interventions
This is a clinical, randomized, crossover, and blinded (participant) study. TTwenty-two individuals diagnosed with Multiple Sclerosis and quadriceps spasticity will participate in each study group. Th
E02.621.820
Sponsors
Universidade Nove de Julho
Universidade Nove de Julho
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants over 18 years of age with a confirmed diagnosis of Multiple Sclerosis and with Relapsing-Remitting, Primary Progressive and Secondary Progressive subtypes; participants who present quadriceps spasticity assessed by the Ashworth scale grade 3; participants who show a quadriceps motor evoked potential response.
Exclusion criteria
Exclusion criteria: Application of phenol, botox, or other procedures that interfere with quadriceps muscle tone within six months or less; recent fracture or surgery in lower limbs; contracture or deformity in the ankles; contraindications for the use of trancranial magnetic stimulation as history of seizures or refractory epilepsy, metal brain implants, brain tumors, or skin lesion at the site of application.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a better response to the high frequency protocol, verifying through the ashworth scale and the motor evoked potential the reduction of spasticity at the end of the study. | — |
Secondary
| Measure | Time frame |
|---|---|
| For the secondary outcome, it is expected to find a better motor evoked potential response in individuals with multiple sclerosis after the application of the high-frequency protocol with transcranial magnetic stimulation. | — |
Countries
Brazil
Contacts
Public ContactFernanda Correa
Universidade Nove de Julho - Uninove
Outcome results
None listed