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Early pulmonary rehabilitation with elastic bands in patients with Exacerbated Chronic Obstructive Pulmonary Disease: Focus on cardiovascular health - vascular function

Early pulmonary rehabilitation with elastic bands in patients with Exacerbated Chronic Obstructive Pulmonary Disease: Focus on cardiovascular health - Cardiac arterial and autonomic function

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2vgq7y
Enrollment
Unknown
Registered
2020-03-11
Start date
2018-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exacerbated Chronic Obstructive Pulmonary Disease unspecified

Interventions

Each new patient included in the study will be randomized and allocated into groups according to whether they are early rehabilitation or not, thus comprising two groups: early rehabilitation group (G
men: 220-age x 0.85) will be respected, as well as dyspnea and lower limb fatigue on the Borg scale between 4-6. Oxygen will be implemented if necessary and SpO2 at rest <85% or there is a drop during
Device
G11.427.410.698.277

Sponsors

Universidade Federal de São Carlos
Lead Sponsor
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Collaborator

Eligibility

Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: Clinical diagnosis of COPD who present exacerbation of the disease according to GOLD (contacted at least 24 hours and at most 48 hours after the start of standard therapy for exacerbation of COPD); spontaneous breathing at the time of the assessment, in conditions to maintain dialogue; those who agree to participate in the research in a free and informed manner.

Exclusion criteria

Exclusion criteria: Drug users who cause chemical dependency; patients with neurological and orthopedic changes; patients using invasive mechanical ventilation; hemodynamic instability; presence of unstable angina; hx of myocardial infarction in the last six months; other lung diseases; patients over the age of 85 years; and those who do not obtain a diagnosis of COPD after pulmonary function assessment, with ratio values ??(forced expired volume in the first second / forced vital capacity) greater than 0.7 and forced expired volume in the first second greater than 80%.

Design outcomes

Primary

MeasureTime frame
It is expected to obtain positive results in arterial stiffness and cardiac endothelial and autonomic functions 30 days after early rehabilitation with elastic bands in the acute exacerbation phase of COPD. It is also expected that the beneficial results of early PR will still be better in the intervention group 30 days after hospital discharge.

Secondary

MeasureTime frame
It is expected to obtain from the study results associations between deltas of arterial stiffness and cardiac endothelial and autonomic functions with variables of functional performance and quadriceps muscle strength of these patients.

Countries

Brazil

Contacts

Public ContactRenata Mendes

Universidade Federal de São Carlos

mendesrg@hotmail.com+55-16-33518448

Outcome results

None listed

Source: REBEC (via WHO ICTRP)