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Effectiveness of green tea and hyaluronic acid in post-tooth extraction repair in patients undergoing radiotherapy

Effectiveness of green tea and hyaluronic acid in post-extraction repair in patients undergoing radiotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2v7d2v4
Enrollment
Unknown
Registered
2025-12-08
Start date
2025-12-17
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adjuvant Radiotherapy

Interventions

This controlled and randomized clinical trial will include 80 patients previously submitted to head and neck radiotherapy who require tooth extraction. Participants will be allocated into four postope
E-CV/AH will use green tea and hyaluronic acid mouthwash every 8 hours for 14 days
G-CV/AH will apply green tea and hyaluronic acid gel five times a day for 14 days
G-CLOX will apply 0.12% chlorhexidine gel with the same frequency. Patients will undergo clin

Sponsors

Faculdade de Odontologia da Universidade Federal de Uberlândia
Lead Sponsor
Universidade Federal de Uberlândia
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with head and neck cancer, of both sexes, over 18 years of age, who require tooth extractions in the context of radiotherapy treatment, either prior to its initiation or afterwards, due to oral cavity preparation or dental emergencies. All participants must agree to take part in the study and provide their signature on the Informed Consent Form

Exclusion criteria

Exclusion criteria: Severely debilitated patients, those who do not accept or do not sign the Informed Consent Form, pregnant or breastfeeding women, individuals with metallic artifacts that impair tomographic analysis, and those who present periapical lesions

Design outcomes

Primary

MeasureTime frame
Degree of healing of post-extraction alveoli in patients undergoing radiotherapy in the head and neck region

Secondary

MeasureTime frame
Comparison of post-extraction alveolar healing between patients using green tea and hyaluronic acid-based products and those using chlorhexidine-based products, both in the form of mouthwash and gel

Countries

Brazil

Contacts

Public ContactPriscilla Soares

Faculdade de Odontologia da Universidade Federal de Uberlândia

pbfsoares@yahoo.com.br+55-34-32258106

Outcome results

None listed

Source: REBEC (via WHO ICTRP)