Metabolic Phenomena
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Have normal blood glucose levels (fasting capillary glucose ranging from 70 to 99 mg/dL); regular breakfast intake; have a Body Mass Index (BMI) between 18.5 and 24.9 kg/m² and a body fat percentage between 20 and 30% for females and between 12 and 20% for males; are between 18 and 60 years old; engage in light physical activity
Exclusion criteria
Exclusion criteria: Smokers; alcohol consumption exceeding 2 drinks per day (> 50g of ethanol/day); presence of type 1 or type 2 diabetes or prediabetes (fasting blood glucose between 100 and 125 mg/dL); first-degree family history of diabetes mellitus; use of medications that affect blood glucose, energy metabolism, or appetite; use of medications, herbs, or diets for appetite and weight reduction; weight instability (gain or loss of approximately 3 kg in the 3 months prior to the start of the study); recent change in level of physical activity; aversion or intolerance to the foods provided in the study; presence or history of digestive, hepatic, renal, cardiovascular, thyroid, or recent inflammatory diseases; diagnosis of cancer in the previous year; history of eating disorders; and being pregnant or lactating
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate postprandial glycemic control, assessed using the trapezoidal method, by determining a variation with a significance level of 0.05 in blood glucose concentration measured through capillary fingerstick at -5 and 0 minutes (fasting state), as well as at 15, 30, 45, 60, 90, and 120 minutes after consuming each beverage or glucose load;To evaluate postprandial insulinemic control, using the trapezoidal method, by determining a variation with a significance level of 0.05 in blood insulin concentration measured through blood collection at 0 minutes (fasting state), as well as at 30, 60, and 120 minutes after consuming each beverage or glucose load | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate appetite control, using the Visual Analogue Scale (VAS) method to assess variations with a significance level of 0.05 in sensations of hunger, satiety, fullness, desire for salty, sweet, fatty, or tasty foods, and food consumption perspective. These sensations will be scored by measuring the distance (in cm) from the 0 point using a ruler at different time points, such as 0 minutes (fasting state), as well as at 15, 30, 45, 60, 90, and 120 minutes after consuming each beverage or glucose load. Additionally, the Composite Satiety Score (CSS) will be calculated at each measurement moment using the following equation: CSS (cm) = (satiety + fullness + (100 - PFC) + (100 - hunger))/4;To evaluate food consumption control, a specific form will be used, which consists of a 24-hour food record after the beverage consumption. This form will record information including the time and location of meals, as well as the types and quantities of foods consumed, which can be measured in grams or household measurements. The data on grams, calorie intake, macronutrients, and dietary fibers recorded in the forms will be analyzed using the Avanutri® software (Rio de Janeiro, Brazil) and will be considered statistically different with a significance level of 0.05 | — |
Countries
Brazil
Contacts
Universidade Federal de Viçosa - Departamento de Nutrição e Saúde