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The effect of different exercise models on elderly people with knee osteoarthritis

Effects of different exercise models with and without blood flow restriction on strength, muscle mass, functionality and pain perception in patients with knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2twzy65
Enrollment
Unknown
Registered
2021-12-20
Start date
2021-08-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

The study will have 4 groups with 15 participants each, as follows: Group 1 control 15 participants, group 2 physiotherapy 15 participants, group 3 strength training associated with blood flow restric
Squat 3 sets of 10 reps
Oyster Hip Abductor Exercise 3 sets of 10 reps
Exercise for hip abductors in lateral decubitus where the elevation of the leg straightened laterally will be performed 3 sets of 10 repetitions
Abdomen and Gluteal Strengthening Exercise with Hip Bridge Movement 3 sets of 10 repetitions
Proprioceptive neuromuscular facilitation exercise for knee flexors
Bipedal Plantar Flexor Exercise 3 sets of 10 repetitions. In weeks 3 and 4, the previous behaviors will be maintained with the addition of 3 sets of 10 to 15 repetitions as tolerated and inclusion of
Dorsiflexion Squats, 3 sets of 10 reps
Knee flexion exercise while standing, 3 sets of 10 repetitions. During weeks 5 to 8, the previous behaviors will be maintained with 3 sets of 15 repetitions and addition of exercises for intrinsic mus
D020370

Sponsors

Universidade São Judas
Lead Sponsor
Grupo de estudos e pesquisa em restrição do fluxo sanguíneo e exercício
Collaborator

Eligibility

Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients of both sexes, aged over 60 years, functional independence, diagnosed with knee osteoarthritis; patients with medical referral for physical therapy treatment; absence of severe cardiovascular or musculoskeletal diseases

Exclusion criteria

Exclusion criteria: Patients with knee arthroplasty, contraindication for the use of pressure cuffs or tourniquets, with peripheral vascular disease, who use anticoagulants, will be excluded; history of deep vein thrombosis, congenital lower limb malformations, diagnosis of fibromyalgia; contraindication to exercise

Design outcomes

Primary

MeasureTime frame
We will investigate the effects of different exercise strategies with and without blood flow restriction on neuromuscular adaptations (Maximum dynamic strength, maximum isometric quadriceps strength and joint range of motion) that will be measured through the test and one repetition maximum (1RM) and isokinetic dynamometer (Variables: Time to Acceleration; Time to Peak Torque; Peak Torque; Peak Torque Angle; Time to Deceleration). Pain will be assessed using the Numerical Pain Scale (END), and functionality will be assessed using the Timed Up and Go (TUG) functional tests, sit and stand, 6-minute walk and treadmill test (speed and time to reach 40% of the heart rate reserve) and finally the thickness and muscle quality of the quadriceps femoris will be measured using ultrasound images. We hope that aerobic and strength training programs with blood flow restriction will be effective in increasing muscle mass, strength, improving function, and reducing the perception of knee pain in a similar but superior way to the conventional physical therapy program

Secondary

MeasureTime frame
The time and level of injury will be checked through the medical diagnosis, the level of physical activity by the international physical activity questionnaire (IPAQ);The drugs in use and interactions between them will be identified. Where initially two questionnaires will be used, the first of which will collect information about the name of the drug, dosage, time of use, and medical prescription. A second questionnaire will consist of 13 questions about the frequency of medication use during the last three months. The analysis of the medication volume of each participant will be separated into categories: 1) medications prescribed for osteoarthritis; 2) prescription drugs for other illnesses; 3) non-prescription medications for osteoarthritis; 4) non-prescription drugs for other illnesses and 5) Alternative pharmaceuticals; 6). To identify drug interactions with great clinical relevance, the Drugs.com application will be used, in which drug interactions will be divided into 4 categories: 1) extreme (interaction with great clinical significance). In this category, drug combinations should be avoided, the risks outweigh the benefits; 2) moderate (moderate clinical significance), where the combination of drugs should be avoided and used only in special cases; 3) little (minimal clinical significance), where risks must be minimized, ie, consider alternative treatments or monitor the patient during treatment; 4) unknown, where no interaction information is described in the literature. If these drug interactions are identified, a theoretical framework survey will be carried out on the interaction

Countries

Brazil

Contacts

Public ContactGiovanna Angeli
giovanna.f.angeli@gmail.com+5511963416674

Outcome results

None listed

Source: REBEC (via WHO ICTRP)