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Impact of daily energy shortage announcements on ICU calorie supply: a pragmatic trial

Impact of daily enunciation of energy deficit on ICU heat supply: a pragmatic trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2sypq9j
Enrollment
Unknown
Registered
2022-07-07
Start date
2021-04-23
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Interventions

The caloric deficit of all participants was collected daily, counted cumulatively and obtained through the proportion between the dietary calories received and the caloric goal desired for the day, wh

Sponsors

Hospital Geral de Fortaleza
Collaborator
Hospital Geral de Fortaleza
Lead Sponsor

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults and seniors, aged 18 years or over; both sexes; being on mechanical ventilation or being intubated within 48 hours of admission; being receiving or starting to receive enteral nutritional therapy within 48 hours of admission; present a diagnosis that possibly requires enteral nutritional therapy for more than 7 days

Exclusion criteria

Exclusion criteria: Subjected to supplemental or total parenteral nutritional therapy in the initial 7 days; submitted to major digestive surgeries; history of short bowel syndrome, inflammatory bowel disease, previous recurrent record of diarrhea; admitted with major digestive bleeds

Design outcomes

Primary

MeasureTime frame
There was no significant difference in the average accumulated caloric deficit between the groups, considering a normal distribution, from the finding of a value of p above 0.05.

Secondary

MeasureTime frame
An increase in caloric supply was observed for patients who used non-nutritional calories (propofol, citrate and glucose serum) during hospitalization - collected and calculated daily - in relation to patients who did not use them, based on the finding of a significant mean difference in this data, through p less than 0.05, considering a normal distribution of the population and applying a confidence interval of 95%.;There was no significant difference between the percentages or between the medians on the occurrence of death between the groups, with p value above 0.05, considering a non-normal distribution for this variable.;There was no significant difference between the medians of the period of stay in the service between the groups, with p above 0.05, considering a non-normal distribution for this variable.;There was no significant difference in the median duration of mechanical ventilation between the groups, with p above 0.05, considering a non-normal distribution for this variable.;There was a significant decrease in the medians of hypoglycemia events in the intervention group compared to the control group, with p less than 0.05, considering a non-normal distribution for this variable, as well as a relevant difference in the proportion of hypoglycemia by groups, noting that more patients in the control group (in percentage) had hypoglycemia events.;There was no relevant percentage difference between the groups regarding the most recurrent reasons for interruption of enteral nutritional therapy. In the same way, there was no relevant difference between the groups regarding the average time on zero diet.;There was no mean difference between the groups regarding protein supply, with p above 0.05, considering a normal distribution.

Countries

Brazil

Contacts

Public ContactComitê e Pesquisa HGF/SUS

Hospital Geral de Fortaleza

cephgf.ce@gmail.com+55-85-31017078

Outcome results

None listed

Source: REBEC (via WHO ICTRP)