Malnutrition
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adults and seniors, aged 18 years or over; both sexes; being on mechanical ventilation or being intubated within 48 hours of admission; being receiving or starting to receive enteral nutritional therapy within 48 hours of admission; present a diagnosis that possibly requires enteral nutritional therapy for more than 7 days
Exclusion criteria
Exclusion criteria: Subjected to supplemental or total parenteral nutritional therapy in the initial 7 days; submitted to major digestive surgeries; history of short bowel syndrome, inflammatory bowel disease, previous recurrent record of diarrhea; admitted with major digestive bleeds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There was no significant difference in the average accumulated caloric deficit between the groups, considering a normal distribution, from the finding of a value of p above 0.05. | — |
Secondary
| Measure | Time frame |
|---|---|
| An increase in caloric supply was observed for patients who used non-nutritional calories (propofol, citrate and glucose serum) during hospitalization - collected and calculated daily - in relation to patients who did not use them, based on the finding of a significant mean difference in this data, through p less than 0.05, considering a normal distribution of the population and applying a confidence interval of 95%.;There was no significant difference between the percentages or between the medians on the occurrence of death between the groups, with p value above 0.05, considering a non-normal distribution for this variable.;There was no significant difference between the medians of the period of stay in the service between the groups, with p above 0.05, considering a non-normal distribution for this variable.;There was no significant difference in the median duration of mechanical ventilation between the groups, with p above 0.05, considering a non-normal distribution for this variable.;There was a significant decrease in the medians of hypoglycemia events in the intervention group compared to the control group, with p less than 0.05, considering a non-normal distribution for this variable, as well as a relevant difference in the proportion of hypoglycemia by groups, noting that more patients in the control group (in percentage) had hypoglycemia events.;There was no relevant percentage difference between the groups regarding the most recurrent reasons for interruption of enteral nutritional therapy. In the same way, there was no relevant difference between the groups regarding the average time on zero diet.;There was no mean difference between the groups regarding protein supply, with p above 0.05, considering a normal distribution. | — |
Countries
Brazil
Contacts
Hospital Geral de Fortaleza