Hypertension
Conditions
Interventions
This is a open-label, two-arm randomised superiority clinical trial. Intervention group: 90 hypertensive patients will receive Short Message Service (SMS) text messages with information about the dise
Sponsors
Juliana Chaves Coelho
Juliana Chaves Coelho
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Age over 18 years; having a diagnosis of arterial hypertension, being treated at the outpatient clinic for at least six months; uncontrolled blood pressure (the average of the office measurements of the last two consultations with systolic blood pressure values greater than 140 mmHg or diastolic blood pressure greater than 90 mmHg will be considered); own a mobile phone; present written comprehension skills; and agree to voluntarily participate in the study, signing the Free and Informed Consent Form
Exclusion criteria
Exclusion criteria: Secondary hypertension; pregnant women; glomerular filtration rate less than 30mL/min.; Body Mass Index greater than 40 kg/m²
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find the blood pressure control outcome, verified by the office measurement, presenting parameters lower than 140 mmHg in systolic blood pressure and lower than 90 mmHg in diastolic pressure or verified by Ambulatory Blood Pressure Monitoring, presenting parameters lower than135 mmHg in systolic blood pressure and less than 85 mmHg in diastolic blood pressure, during wakefulness. The greater weight will be attributed to the outcome measured by Ambulatory Blood Pressure Monitoring during wakefulness | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find reductions in the mean values of blood pressure, by measuring in the office and by Ambulatory Blood Pressure Monitoring.;It is expected to identify the blood pressure control evaluated by the parameters of the "Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association-2017", whose parameters consider systolic blood pressure lower than 130mmHg and diastolic blood pressure lower than 80mmHg;It is expected to identify adherence to treatment, measured by the Morisky Four-Item Therapeutic Adherence Scale (MMAS-4) and, directly, antihypertensive drugs and their metabolites in urine will be evaluated by high performance liquid chromatography associated with mass spectrometry;It is expected to evaluate the white coat effect, defined by the difference in systolic and diastolic blood pressures greater than 20 mmHg and 10 mmHg, respectively, in the office pressure measurement, when compared with those recorded by ABPM;It is expected to perform subgroup analyses, evaluating the primary outcome for different groups, according to sex, age, race, obesity, treatment adherence and disease history. | — |
Countries
Brazil
Contacts
Public ContactJuliana Coelho
Escola de Enfermagem da Universidade de São Paulo
Outcome results
None listed