Gingivitis
Conditions
Interventions
Test group: 14 periodontitis subjects, of both genders, will receive conventional periodontal treatment (Oral Hygiene instructions plus Scaling and Root planing) divided in 4 weekly sessions of 30 min
Control group: 14 periodontitis subjects, of both genders, will receive conventional periodontal treatment (Oral Hygiene instructions plus Scaling and Root planing) divided in 4 weekly sessions of 30
Procedure/surgery
Dietary supplement
G07.203.300.456.500
Sponsors
Universidade Veiga de Almeida
Universidade Veiga de Almeida
Eligibility
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Volunteers must present Periodontitis; presence of probing pocket depth > 3 mm in association with clinical attachment loss > 3 mm in at least 2 sites of 2 non-adjacent teeth; They must also present more than 20 teeth; age between 30 to 70 years old.
Exclusion criteria
Exclusion criteria: Cigarete smokers; history of previous periodontal treatment; antibiotics use within the past 6 months; pregnancy; presence of acute or necrotizing lesions; history of diabetes; rheumatic fever; neurological deficiencies; immunological diseases; use of medications that affect periodontal tissues such as phenytoin, cyclosporine, nifedipine and anti-inflammatories.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Statistically significative clinical attachment level average reduction in the pre and post treatment measurements (in milimeters). Verified by clinical probing in 4 sites per tooth using standard periodontal probe; Data collected pre-treatment and 30, 60 and 90 days after the intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome 1: Statistically significative probing pocket depth average reduction in the pre and post treatment measurements (in milimeters); Verified by clinical probing in 4 sites per tooth using standard periodontal probe; Data collected pre-treatment and 30, 60 and 90 days after the intervention.;Secondary outcome 2: Statistically significative visible biofilm reduction in the pre and post treatment measurements; Verified by visual analysis as absent or present in 4 sites per tooth and the final score is the percentage of tooth surfaces with biofilm; Data collected pre-treatment and 30, 60 and 90 days after the intervention. ;Secondary outcome 3: Statistically significative bleeding on probing reduction in the pre and post treatment measurements; Verified by gingival probing in 4 sites per tooth using standard periodontal probe and the final score is the percentage of bleeding sites; Data collected pre-treatment and 30, 60 and 90 days after the intervention.;Secondary outcome 4: Statistically significative microbial level reduction in the pre and post treatment measurements; Evaluation of biofilm collected from 3 teeth per patient by means of checkerboard DNA-DNA hybridization technique, considering the presence and quantity of 40 bacteria; Data collected pre-treatment and 30, 60 and 90 days after the intervention. | — |
Countries
Brazil
Contacts
Public ContactAntonio;Antonio Canabarro;Canabarro
Universidade Veiga de Almeida;Universidade Veiga de Almeida
Outcome results
None listed