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Evaluation of blood microcirculation by cheek laser Doppler flowmetry in patients undergoing chemotherapy or radiotherapy

Laser Doppler Flowmetry evaluation in the genius region in patients undergoing antineoplastic therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-2ryhcv
Enrollment
Unknown
Registered
2020-01-29
Start date
2015-06-08
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck Neoplasms

Interventions

506/5000 Patient assessments prior to initiation of antineoplastic therapy and during the intensive phase of head and neck radiotherapy or chemotherapy, at 7-point chemotherapy (11 patients) and 8-poi
the WHO (World Health Organization) and OMAS (Oral Mucositis Assessment Scale) scales for the evaluation of the degree of mucositis
and Visual Analog Scale (VAS) for the evaluation of oral mucosa pain.
Device
C76.8

Sponsors

Universidade de São Paulo - Campus Bauru
Lead Sponsor
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of malignant tumor; Therapeutic regimen associated with high risk of developing oral mucositis. Standard chemotherapy and or head and neck radiotherapy; Over age 18 years.

Exclusion criteria

Exclusion criteria: Pregnancy; Diabetic; Smoker Patients with uncontrolled blood pressure

Design outcomes

Primary

MeasureTime frame
Alteration of blood microcirculation in the genial region during chemotherapy and radiotherapy determined by laser doppler flowmetry at baseline and at end of study   oral mucositis (WHO and OMAS) and AVS.

Secondary

MeasureTime frame
Alteration in the blood microcirculation of the genian region, increase of the degree of oral mucositis and increase of value of the AVS scale.

Countries

Brazil

Contacts

Public ContactPaulo Santos

Universidade de São Paulo - Campus Bauru

paulosergiosilvasantos@gmail.com+55-14-32266113

Outcome results

None listed

Source: REBEC (via WHO ICTRP)