The use of Alpinia zerumbet gel-cream to manage pain and symptoms related to temporomandibular disorders

Clinical evaluation of the use of alpinia zerumbet gel-cream for use in patients with muscle temporomandibular dysfunction: randomized clinical study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

REBEC

Registry ID

RBR-2rtpqt8

Enrollment

Unknown

Registered

2025-06-17

Start date

2025-09-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular Joint Syndrome

Interventions

A randomized, controlled, double-blind, longitudinal clinical trial. In the first stage, 84 participants will be selected and divided into three groups of 28 each, where one will have as an interventi

E02.760.169.063.500.387

Eligibility

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Individuals of both sexes; aged between 18 and 70 years; with at least 20 natural dental elements (10 on each side); diagnosed with muscular type temporomandibular disorders (TMD)

Exclusion criteria

Exclusion criteria: Individuals with any inability to answer questions asked during care; patients who are already using therapeutic ultrasound or another type of therapy for muscle fatigue

Design outcomes

Primary

Measure	Time frame
It is expected to find an improvement in chewing performance by scanning mascara gum for chewing cycles.	—

Secondary

Measure	Time frame
It is expected to verify an improvement in pain using an algometer and EVA scale, in muscle activity through electromyography, in bite force through a dynamometer, in quality of life through the SF-26 and possible adverse effects through the Naranjo algorithm.	—

Countries

Brazil

Contacts

Public ContactPatricia Serpa

Universidade Federal do Ceará

patriciafserpa@gmail.com+55-85-33668275

Outcome results

None listed

Source: REBEC (via WHO ICTRP)