Apnea Sleep Obstructive
Conditions
Interventions
This study is a randomized controlled clinical trial, with the aim of evaluating the effects of a strength training program on variables such as cardiac autonomic modulation, hemodynamic variables, bo
E02.760.169.063.500.387.875
Sponsors
Pronto S.Cardiologico de Pe.Prof.Luiz Tavares - PROCAPE
Universidade Federal de Pernambuco
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients of both sexes will be included; with obstructive sleep apnea diagnosed through full-night polysomnography; with moderate to severe disease severity (Apnea-hypopnea index = 15 events/hour); who are over 18 years old; and are not undergoing prior treatment for obstructive sleep apnea; patients must have a body mass index = 25 kg/m²
Exclusion criteria
Exclusion criteria: Patients with uncontrolled hypertension (160mmHg systolic and 100mmHg diastolic); musculoskeletal diseases that prevent the intervention; as well as patients with chronic obstructive pulmonary disease; and patients participating in other supervised or unsupervised interventions; as well as those using continuous positive airway pressure, will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction of at least 4 events per hour in the apnea-hypopnea index (AHI), assessed by full nocturnal polysomnography, which quantifies the episodes of apnea and hypopnea per hour of sleep, is expected. The assessment will be performed one week before and two weeks after the strength training intervention.;A 10% reduction in systolic (SBP) and diastolic (DBP) blood pressure is expected, as assessed by 24-hour ambulatory blood pressure monitoring (ABPM 04). Measurements will be taken during the day and at night, one week before and two weeks after the strength training intervention.;A reduction of at least 10% in pulse wave velocity (PWV) is expected, as assessed using the SphymoCor device, which measures arterial elasticity and provides data on arterial stiffness. The assessment will be performed one week before and two weeks after the strength training intervention.;An improvement in autonomic modulation is expected, reflected in an increase in heart rate variability (HRV), assessed using the Polar Vantage M2 monitor. HRV will be measured at rest, one week before and two weeks after the strength training intervention, indicating an improved balance between the sympathetic and parasympathetic systems of the autonomic nervous system. | — |
Secondary
| Measure | Time frame |
|---|---|
| t is expected to find a 10% increase in the strength of the resistant muscles, assessed by measuring the maximum expiratory pressure (PEMAX) and maximum inspiratory pressure (PIMAX) using the manovacuometer. The evaluation will be performed one week before and two weeks after the strength training intervention. | — |
Countries
Brazil
Contacts
Public ContactJosé Almeida
Laboratório do Sono e Coração - PROCAPE
Outcome results
None listed