Fatty liver degeneration, not elsewhere classified
Conditions
Interventions
Experimental group: 20 patients with non-alcoholic steatohepatitis received an individualized diet (1,651.34 ± 263.25 kcal, 47% carbohydrate, 28% lipid, 25% protein and 31g fiber) plus general nutriti
Behavioural
G07.203.650.240
Sponsors
Faculdade de Medicina de Universidade Federal de Juiz de Fora
Faculdade de Medicina de Universidade Federal de Juiz de Fora
Eligibility
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: Age greater than 18 years; both genders; previous diagnosis of non-alcoholic steatohepatitis by means of liver biopsy.
Exclusion criteria
Exclusion criteria: Presence of chronic hepatitis B; chronic hepatitis C; autoimmune diseases of the liver; hemochromatosis; HIV-1 and 2-infected patients; patients with drug-induced; alcohol-induced liver disease (greater than 30 g / day in men or greater than 20 g / day in women); use of antibiotics in the two months prior to inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modulation of the fecal microbiota: result described in micro-gas density (x 108 g-1 cells), by fluorescent in situ hybridization technique ;Alteration of the bacterial overgrowth frequency in the small intestine: result expressed as a percentage and evaluated by respiratory test of exhaled hydrogen and methane. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in laboratory parameters: evaluation of hepatic transaminases, glycemic profile and lipid profile. Blood samples were collected and analyzed according to laboratory routine.;Change in anthropometric measurements and body composition: body weight, waist circumference, percentage of body fat and body mass index, by means of digital scale, tape measure and electric bioimpedance. | — |
Countries
Brazil
Contacts
Public ContactAna Paula Moreira
Universidade Federal de Juiz de Fora
Outcome results
None listed