Laser therapy in post-surgery care for head and neck

The role of Photobiomodulation in postoperative care for head and neck surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

REBEC

Registry ID

RBR-2r5qwyj

Enrollment

102

Registered

2026-04-16

Start date

2024-05-15

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Squamous Cell Carcinoma of Head and Neck Neoplasms

Interventions

This is a randomized controlled open label clinical trial with two parallel arms. A total of 102 participants will be allocated in a one to one ratio to the intervention group and the control group, w

Eligibility

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Both genders; age over 18; patients undergoing surgical treatment for squamous cell carcinoma of the upper aerodigestive tract

Exclusion criteria

Exclusion criteria: Salvage surgery; previous radiotherapy or chemotherapy; palliative surgery; diagnostic surgical procedure; surgical procedure to correct complications; Eastern Cooperative Oncology Group (ECOG) 3 or 4; Body Mass Index (BMI) less than 18; and any other surgical procedure that does not have an oncological curative purpose

Design outcomes

Primary

Measure	Time frame
Evaluate the difference in the incidence of postoperative complications by recording complications and subsequently comparing between the study arms.	—

Secondary

Measure	Time frame
Evaluate lymphedema by recording cervical and facial circumference measurements, photographic records, and drain output.;Evaluate the progression of pain using the visual analog scale for pain and recording the use of analgesics with their respective doses.;Assessment of the difference in quality of life, both between the study arms and in relation to the patient's progression, by applying the EORTC QLQ-C30 and EORTC QLQ – H&N35 quality of life questionnaires during the immediate and late postoperative periods.	—

Measure

Time frame

Evaluate lymphedema by recording cervical and facial circumference measurements, photographic records, and drain output.;Evaluate the progression of pain using the visual analog scale for pain and recording the use of analgesics with their respective doses.;Assessment of the difference in quality of life, both between the study arms and in relation to the patient's progression, by applying the EORTC QLQ-C30 and EORTC QLQ – H&N35 quality of life questionnaires during the immediate and late postoperative periods.

—

Countries

Contacts

Public ContactMarianne Nakai

Irmandade da Santa Casa de Misericórdia de São Paulo

mynakai@gmail.com+55(11)976758176

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: May 1, 2026