Chronic Cough
Conditions
Interventions
This is a randomized, placebo-controlled clinical trial involving 120 patients with chronic refractory cough for more than one year, divided into four groups of 30 participants each. Two groups will r
Sponsors
Escola Paulista de Medicina da Universidade Federal de São Paulo
Escola Paulista de Medicina da Universidade Federal de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Individuals of both sexes; over 18 years of age; with a complaint of Refractory Chronic Cough for more than six months associated with underlying comorbidities who were in treatment for at least two months; using medications such as antibiotics, inhaled bronchodilators, inhaled steroids, oral corticosteroids, proton pump inhibitors, antihistamines; neuromodulators such as Morphine, Gabapentin and Pregabalin
Exclusion criteria
Exclusion criteria: Individuals with untreated comorbidities associated with Chronic Cough; those taking angiotensin-converting enzyme inhibitor medications; untreated infections in the last two months; individuals with lung conditions, such as lung cancer, lung metastases, previously diagnosed endobronchial lesions, and lesions resulting from thoracic radiotherapy; limiting neurological diseases; and smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effectiveness of speech therapy in reducing refractory chronic cough using self-assessment instruments | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the change in the severity of chronic cough before and after the intervention and to verify the perception of laryngeal hypersensitivity through self-assessment questionnaires | — |
Countries
Brazil
Contacts
Public ContactMaria Christina Casmerides
Escola Paulista de Medicina da Universidade Federal de São Paulo
Outcome results
None listed