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Long-term effects of functional training in the prevention of heart problems in women with Breast Cancer undergoing Chemotherapy: randomized clinical trial

Chronic effects of functional training on the prevention of subclinical cardiotoxicity in women ith Breast Cancer undergoing Chemotherapy: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2pzz8fx
Enrollment
Unknown
Registered
2025-12-15
Start date
2024-04-04
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Quality of Life

Interventions

This is a non-randomized clinical trial involving 20 women undergoing chemotherapy, divided into two groups. The experimental group (EG, n=10) participated in three weekly functional training sessions
OMNI-GSE 3 to 5), executed in three sets of 30 seconds with 30-second rest intervals between sets. The third phase comprised twenty-five minutes of strength training (neuromuscular 2
OMNI-GSE 5 to 7), also carried out in three sets of 30 seconds with 30-second rest periods. The final phase included five minutes of cardiometabolic training (OMNI-GSE 7 to 10), initially performed in

Sponsors

Programa de Pós-Graduação em Educação Física - PPGEF
Lead Sponsor
Programa de Pós-Graduação em Educação Física - PPGEF
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women diagnosed with HER2+ breast cancer (negative, positive, and/or triple positive for hormonal receptors);aged between 18 and 50 years;chemotherapy treatment conducted with monoclonal antibodies and/or their derivatives with the first cycle completed or ongoing;who have medical clearance to undergo the intervention protocol;normocardic;normotensive;with a ventricular ejection fraction above 50%;sedentary in the last three months prior to the start of the intervention protocol;without cognitive; functional;neuronal deficits;signing the informed consent form (ICF)

Exclusion criteria

Exclusion criteria: Women who have other types of diagnosed neoplasms;with metastatic lesions;who have undergone bilateral mastectomy;who receive chemotherapy treatment with anthracyclines alone;who change the type of chemotherapy during the application of the intervention protocol;who undergo only radiotherapy and/or hormone therapy;women with a diagnosis of previous cardiovascular disease;who have more than 25% absence in the intervention protocol;and those who die during the course of the protocol

Design outcomes

Primary

MeasureTime frame
It is expected to observe a long-term cardioprotective effect provided by functional training in women diagnosed with breast cancer undergoing chemotherapy, during the pre- and post-intervention period over 3 months

Secondary

MeasureTime frame
It is expected to observe an improvement in functional capacity, quality of life, sleep quality, and muscle strength both in the pre-intervention and post-intervention periods

Countries

Brazil

Contacts

Public ContactAna Luiza Setton

Programa de Pós-Graduação em Educação Física - PPGEF

settonana@gmail.com+55(79)99184359

Outcome results

None listed

Source: REBEC (via WHO ICTRP)