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Mouthwashes for treatment of nas breath

Chemical control of oral halitoses by mouthwashes: evaluation by gas chromatography and organoleptic test

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2phxzm
Enrollment
Unknown
Registered
2018-08-17
Start date
2012-04-04
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis

Interventions

The effectiveness of mouthwashes on the market, with alcohol and without alcohol, was evaluated in order to reduce the oral breath and to measure how long the effect was lasting, compared to a control
Chlorhexidine digluconate (0.12%) - bis-biguanide (no alcohol), 21 participants, both genders
Essential Oils (Thymol, Menthol, Eucalyptol, Methyl Salicylate) with alcohol and zinc chloride, 21 participants, both genders
Essential Oils (Thymol, Menthol, Eucalyptol and Methyl Salicylate) without alcohol, 21 participants, both genders.
Drug
D02.078.370.141.100

Sponsors

Faculdade De Odontologia de Ribeirão Preto
Lead Sponsor
Faculdade De Odontologia de Ribeirão Preto
Collaborator

Eligibility

Age
12 Years to 50 Years

Inclusion criteria

Inclusion criteria: Presence of at least 20 natural teeth; Good oral hygiene; Absence of periodontal disease, xerostomia, or any chronic inflammatory process; Patients with halitosis of intra-oral cause.

Exclusion criteria

Exclusion criteria: Smokers; Alchoolics; Pregnant or lactating; Carriers of systemic diseases (hepatic, renal, diabetes); Presence of pharyngeal or tonsillar infection; Upper or lower respiratory tract inflammation; Carriers of removable prostheses, clinically unsatisfactory fixed prostheses, dental caries, lesions on the buccal mucosa; Individuals who have used antibiotics in the last 3 months.

Design outcomes

Primary

MeasureTime frame
Reduction or elimination of oral halitosis with mouthwashes with and without alcohol.;Only the product with the essential oils, alcohol and zinc chloride in its formula was effective for reducing breath.

Secondary

MeasureTime frame
Non-alcoholic mouthwashes are expected to reduce oral halitosis more effectively than those with alcohol in the composition.;The alcohol-free mouthwashes obtained the worst results, and the essential oils allowed the initial values of halitosis to increase after 3 hours.

Countries

Brazil

Contacts

Public ContactVinicius Pedrazzi

Faculdade De Odontologia de Ribeirão Preto

pedrazzi@forp.usp.br+55 16 3315-4008

Outcome results

None listed

Source: REBEC (via WHO ICTRP)