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Evaluation of histological measurement of different graft associations in maxillary sinus after surgery for sinus cavity elevation in antral cavities

Histomorphometric evaluation of different graft associations for maxillary sinus elevation in antral cavities - L-PRF Leukocyte- and Platelet-Rich Fibrin

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2pbbrvg
Enrollment
Unknown
Registered
2021-11-08
Start date
2020-01-13
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone resorption

Interventions

A total of 36 patients underwent the sinus lifting procedure ato ne side, through the side window and randomly filled with the following materials (n = 12 patients / group): Group 1 - Bio-Oss + autoge

Sponsors

Faculdade São Leopoldo Mandic
Lead Sponsor
Associação Brasileira de Odontologia - MT
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The study included patients older than 18 years, without pathologies of the maxillary sinus, with maxillary sinuses classified as wide (Chan et al. 2014), and with a posterior bone height below 3 mm in the 2nd premolar and 1st molar region.

Exclusion criteria

Exclusion criteria: The exclusion criteria applied were patients with a chronic disease that would contraindicate the surgical procedure, such as uncontrolled diabetes, hypertension and head/neck radiation, smokers (more than 5 cigarettes per day), and patients with habits that could interfere with the treatment, such as alcoholism and drug use, use of prolonged bisphosphonate therapy, and/or a history of previous surgical procedure for maxillary sinus graft.

Design outcomes

Primary

MeasureTime frame
Histologically assess whether there is an increase in bone neoformation in surgeries to elevate the maxillary sinus, after 8 months of bone graft, when associated with xenogenic biomaterial (Bio-Oss) or L-PRF (group 2) or autogenous bone (group 3). The amount of newly formed bone will be measured in the trephine, in square millimeters.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactElizabeth Martinez
elizabeth.martinez@slmandic.edu.br+55 11 996252801

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 18, 2026