Eosinophilic Esophagitis
Conditions
Interventions
Clinical, prospective, open trial study. A total of 27 patients with the diagnosis of Eosinophilic Esophigitis were included. After the diagnosis, All of the patients received treatment with proton pu
Sponsors
Hospital Santa Casa de Misericórdia de Porto Alegre
Hospital Santa Casa de Misericórdia de Porto Alegre
Eligibility
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: Children and Adolescents aged 1month to 18 years who were referred to the pediatric endoscopy unit were included. Patients were included when they met the diagnosis criteria for Eosinophilic esophagitis (presenting at least one symptom of esophageal dysfunction; esophageal biopsy with more than 15 eosinophil per high power field) and absence of gastric and duodenal eosinophilia. 4 to 6 biopsies were randomly obtained from the distal and middle esophagus. Biopsies specimens were also obtained from the antrum and duodenum to exclude gastritis and eosinophilic gastroenteritis
Exclusion criteria
Exclusion criteria: Children were excluded if they had received prior and recent (up to 1 month before the endoscopy) treatment with proton pump inhibitor; corticosteroids or elimination diet; or if they presented duodenal or gastric eosinophilia or viral, fungal or caustic esophagitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a therapeutic response in pediatric patients with eosinophilic esophagitis who received proton pump inhibitor medication | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find demographic associations in pediatric patients with eosinophilic esophagitis that received proton pump inhibitors medication. Its is expected to find clinical, endoscopic and histological associations in pediatric patients with eosinophilic esophagitis who received proton pump inhibitor medication | — |
Countries
Brazil
Contacts
Public ContactLuiza Salgado Nader
Hospital Santa Casa de Misericórdia de Porto Alegre
Outcome results
None listed