Obesity
Conditions
Interventions
Behavioural
E02.065.062.750
Q65.070
The sample will consist of adult patients of both sexes, aged between 18 and 40 years, indicated for gastroplasty by the Capella technique, at the Bariatric Clinic of the city of Piracicaba (SP). Two
Procedure/surgery
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: The inclusion factors will be: young adults between the ages of 18 and 40, of both sexes, with indication of gastroplasty
Exclusion criteria
Exclusion criteria: The exclusion factors of the sample will be: diagnosis of chronic diseases such as epilepsy, cancer, rheumatoid arthritis; bucco-dentofacial diseases or trauma; use of tobacco or illicit drugs; Diseases that alter the quantity and quality of secreted saliva, such as Sjögren's syndrome, systemic lupus erythematosus and sarcoidosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: We expect to see whether surgical treatment (gastroplasty) has positive impacts on oral health. Method used: Before and after bariatric surgery, the volunteers will be evaluated for oral health by the periodontal index and DMFT. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome: It is also expected to better understand the role of oral bacteria in obesity and whether they could serve as biological indicators for overweight. Method used: Quantitative PCR for the detection and quantification of microorganisms.;Expected outcome: The occurrence of cytogenetic alterations in individuals submitted to gastropasty. Method used:Test of micronuclei in oral mucosa cells;Expected outcome: Verify the expression of anti-and pro-inflammatory cytokines against an improvement in insulin resistance, contributing to the prevention and early diagnosis of oral disorders related to morbid obesity and diabetes mellitus. Method used: Analysis of salivary inflammatory cytokines. | — |
Countries
Brazil
Contacts
Public ContactPaula Castelo
Universidade Federal de São Paulo (UNIFESP)
Outcome results
None listed