Stomach Neoplasms
Conditions
Interventions
This is a longitudinal, randomized, controlled, double-blind study, with a sample of 300 patients undergoing routine upper digestive endoscopy, randomized 1 by 1, through a draw into two arms to recei
E01.390.500
Sponsors
Instituto Hospital de Base do Distrito Federal
Instituto de Gestão Estratégica de Saúde do Distrito Federal
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Outpatient care for diagnostic upper gastrointestinal endoscopy; age greater than or equal to 18 years; both sexes
Exclusion criteria
Exclusion criteria: Patients who did not sign the Informed Consent Form; those who had forms filled out incompletely; patients with malignant gastrointestinal tract diseases; and neurological diseases; with an indication of therapeutic procedures at the time of the examination; the presence of food residues in the esophagus or stomach
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Better efficacy of the solution containing mucolytic agents with antifoams in clearing mucus and bubbles from the gastric mucosa during diagnostic upper digestive endoscopy ;Finding outcome 1: Mucolytic agents with antifoam did not show superiority over a group with antifoam alone. More studies are needed to prove the real benefit of this combination | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: Compare the mucosal visibility index, the volume of liquids needed to achieve adequate mucosal vision, and the total procedure time between the two solutions ;Finding Outcome 2: Compared to placebo, the simethicone plus NAC solution significantly improved visibility in the antrum. Further studies are needed to evaluate the optimal doses, volumes, and administration times of pre-endoscopic solutions and determine the impact of using these solutions on the lesion detection rate | — |
Countries
Brazil
Contacts
Public ContactDaniela Louro
Instituto Hospital de Base
Outcome results
None listed