Cronic pain
Conditions
Interventions
This is a two-arm, double-blind, randomized controlled clinical trial. The experimental group will be 54 individuals consuming 2 g of omega-3, divided into 1 g at lunch and 1 g at dinner and a control
Sponsors
Universidade do Sul de Santa Catarina - Unisul
Universidade do Sul de Santa Catarina - Unisul
Eligibility
Age
20 Years to 59 Years
Inclusion criteria
Inclusion criteria: Volunteer of both sexes; age between 20 and 59 years; diagnosed with obesity grade I and II; at risk of metabolic complications associated with obesity; with obesity-related chronic musculoskeletal pain; and who sign the informed consent
Exclusion criteria
Exclusion criteria: Volunteers using anti-inflammatory drugs (steroidal and non-steroidal) and analgesics; volunteers already taking omega-3 supplementation and volunteers who had corona virus disease 19 during the study will be excluded from the analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that there will be a reduction in chronic pain (assessed using the Mcgill questionnaire, pain scale and biochemical parameters) and obesity, using body mass index, waist circumference and percentage of relative body fat and biochemical data) , as well as the improvement in quality of life assessed by the SF-36 quality of life questionnaire after omega-3 supplementation in patients with obesity-related chronic pain. It is intended to contribute with scientific evidence on the benefits of using omega-3 for the treatment of chronic pain in patients with obesity, since being overweight can trigger chronic pain, especially musculoskeletal pain, which can impact the quality of life of these individuals. . | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that this research will also contribute to the knowledge of the mechanisms of action of omega-3 supplementation on the modulation of inflammatory mediators such as adiponectin, leptin, tumor necrosis factor, interleukin-6, interleukin-10 and protein C- reactive. It is expected to contribute to the deepening of discussions on the benefits of supplementation with omega-3 to reduce body weight and consequent reduction of pain associated with obesity from the comparison of data obtained before and after intervention. | — |
Countries
Brazil
Contacts
Public ContactFranciane Bobinski
Universidade do Sul de Santa Catarina - Unisul
Outcome results
None listed