Enteral Nutrition
Conditions
Interventions
The study will be Uniblind. The expected number of participants is 117 patients, 58 in the intervention group and 59 in the control group. Individuals who are going to start nutrition by gastric or en
G07.203.300.456.500
Sponsors
Universidade Federal do Paraná
Pontifícia Universidade Católica do Paraná
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: ndividuals of both sexes; aged 18 years or older; who are hospitalized in an intensive care unit; who have indication of enteral nutrition via nasogastric, nasoenteral or gastrostomy tube will be included
Exclusion criteria
Exclusion criteria: Individuals who do not present hemodynamic conditions to receive enteral diet, patients with lesions in the gastrointestinal tract that make it impossible to receive enteral diet, patients who are in palliative treatment, who undergo immunosuppressive treatment, who have heart valve prosthesis or valve graft, who have a history of endocarditis, history of rheumatic fever, recent postoperative period of intestinal anastomosis, biliary tract and pancreas surgery, intestinal ischemia, patients with hematological and rheumatological diseases, as recommended by the 2018 Brazilian guideline for nutritional therapy in critically ill patients (BRASPEN, 2018)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in the number of infections occurring within the ICU for patients who use probiotics associated with enteral nutrition compared to the control group, observed by the percentage difference in the number of infections that will occur in the research participants | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in capillary glycemia in patients who use probiotics associated with enteral nutrition compared to the control group, observed by the percentage difference in insulin use to patients. ;It is expected to find a reduction in the length of stay in the ICU for patients receiving probiotics compared to the control group, observed by the difference in the number of days they are hospitalized in the intensive care unit;It is expected to find a reduction in the duration of mechanical ventilation in patients receiving probiotics compared to the control group, observed by the difference in the number of days they are on mechanical ventilation | — |
Countries
Brazil
Contacts
Public ContactJanaina Pocidoni
Universidade Federal do Paraná
Outcome results
None listed