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Analysis of microorganisms existing in denture wearers before and after the use of two adhesives

Oral microbiota analysis of conventional complete dentures wearers before and after the use of two adhesives

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2kpz5j
Enrollment
Unknown
Registered
2015-08-17
Start date
2015-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mouth, Edentulous

Interventions

Participants (n=20) will receive new dentures. After a period of adjustment (30 days), the research subjects will be submitted to an initial examination (collection of dental plaque and saliva for ana
Protocol 2- use of adhesive 2 during the first 15 days, followed by no adhesive for the next 15 days, and subsequent use of adhesive 1 for another 15 days. Four collections of oral microorganisms wil
Other

Sponsors

Universidade Estadual Paulista - UNESP
Lead Sponsor
CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Adult individuals; receptive and mentally agile; good understanding of spoken Portuguese; with availability to attend evaluations during the experimental phase; alveolar ridges with normal resilience and volume

Exclusion criteria

Exclusion criteria: Systemic debilitations; use of antibiotics at the moment of inclusion in the study and for 3 months prior to the first assessment or sample collection; previous use of denture adhesives

Design outcomes

Primary

MeasureTime frame
Verification of the difference in microorganisms in the mouth of denture wearers when there is use of prosthetic adhesives, using the HOMINGS analysis (allow to identify wide variety of microorganisms) in 20 denture wearers, from the finding of a range of at least 5% between the control analysis and after use of adhesives by the participants.

Secondary

MeasureTime frame
No difference of microorganisms in the mouth of denture wearers when there is use of prosthetic adhesives, using the HOMINGS analysis (allow to identify wide variety of microorganisms) in 20 denture wearers, from the finding of a range of at least 5% between the control analysis and after use of adhesives by the participants.

Countries

Brazil

Contacts

Public ContactMarco Compagnoni

Universidade Estadual Paulista - UNESP

compagno@foar.unesp.br+551633016411

Outcome results

None listed

Source: REBEC (via WHO ICTRP)