rheumatoid arthritis
Conditions
Interventions
G03.495.710
D09.546.359.448.500
Cross-sectional study in 200 patients with rheumatoid arthritis. Medical consultations were carried out for determination of weight, height, waist circumference, visual analog scale, number of swollen
Other
D12.644.276.374.500.800
Sponsors
Universidade Estadual de Londrina
Fundação Araucária
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with rheumatoid arthritis who meet the criteria of the American College of Rheumatology 2010.
Exclusion criteria
Exclusion criteria: Patients with other autoimmune diseases, kidney, heart, liver, diabetes, acute or chronic infectious diseases; use of metformnas and statins, supplements with antioxidant activity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients with rheumatoid arthritis and insulin resistance have increased disease activity as measured by the Disease Activity Score 28 joints (DAS28); inflammatory process at a higher intensity, measured by ESR, C-reactive protein and serum levels of tumor necrosis factor alpha ; and unfavorable redox status assessed by advanced oxidation protein products, plasma total antioxidant capacity when compared to patients with rheumatoid arthritis without insulin resistance. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients using anti-tumor necrosis factor had lower plasma levels of tumor necrosis factor alpha therapy.;Patients taking anti tumor necrosis factor had higher plasma levels of tumor necrosis factor therapy than those who did not use. | — |
Countries
Brazil
Contacts
Public ContactAndréa Simão
Universidade Estadual de Londrina
Outcome results
None listed