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Analysis of gum substances in patients who underwent Home Teeth Whitening

Analysis of acute phase markers in patients undergoing at-Home Dental Bleaching:a blinded randomized controlled clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-2hmgr4d
Enrollment
Unknown
Registered
2025-07-24
Start date
2025-05-06
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation Mediators

Interventions

Patients will be randomly assigned to three groups (N=20) using the randomizer.org website. The groups will be control (CT), carbamide peroxide (CP) and hydrogen peroxide (HP). Patients in the PC grou
IDE Interstate, Amityville, NY, USA) will be inserted 1 to 2mm into the sulcus for 15 seconds. One strip will be used per site, with six sites per patient: maxillary central incisor, maxillary and man
E06.420.750

Sponsors

Universidade de Brasilia/ Departamento de odontologia
Lead Sponsor
Universidade de Brasilia/ Departamento de odontologia
Collaborator

Eligibility

Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 40; both sexes; healthy; without active caries or periodontal disease and interested in whitening their teeth will be selected

Exclusion criteria

Exclusion criteria: Use of antimicrobials and immunosuppressants for less than three months; smokers; hospitalization and dental treatment within three months prior to the start of the study; pregnant and breastfeeding women; patients with unsatisfactory restorations; severe fluorosis; tetracycline staining

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: An increase in inflammation markers in crevicular fluid is expected after dental whitening, using the ELISA test, starting at 10% in relation to the patient's initial parameter

Secondary

MeasureTime frame
Expected outcome 2: A slight increase in gingival edema is expected to be found after tooth whitening through clinical inspection

Countries

Brazil

Contacts

Public ContactAna Carolina Santos

Faculdade de Ciências da Saúde da Universidade de Brasilia

carolpasmadjian@gmail.com+55(61)3107-1947

Outcome results

None listed

Source: REBEC (via WHO ICTRP)