Latent tuberculosis infection
Conditions
Interventions
The study will consist of two phases. In the first phase, we will conduct a survey to identify the bottlenecks in the different steps since the identification of contacts to the treatment of those who
Behavioural
I02.233.332
SH1.030.030.050
Sponsors
Rio de Janeiro Secretaria Municipal de Saúde
Centro de Pesquisas Aggeu Magalhães (CPqAM)
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD)
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: In the first phase (diagnosis of the bottlenecks) Subjects with active pulmonary tuberculosis and their household contacts aged 18 or over; health care workers who assist tuberculosis patients In the second phase (intervention): Household contacts of patients with active pulmonary tuberculosis; any age; health care workers who assist tuberculosis patients
Exclusion criteria
Exclusion criteria: Only in the first phase: not agreement to participate or sign the informed consent. No associated co-morbidity prevents the participant to take part in the study (mainly concerning active tuberculosis screening).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 20% increase in the proportion of subjects (among all identified contacts) that start latent tuberculosis infection treatment verified through the contact registry book | — |
Secondary
| Measure | Time frame |
|---|---|
| Increase in number of identified contacts/index-case verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome. ;Increase in the proportion of identified contacts submitted to tuberculin skin testing verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome.;Increase in the proportion of contacts submitted to tuberculin skin testing with reading verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome.;Increase in the proportion of contacts with positive tuberculin skin testing who undergo complete examination to rule out active tuberculosis verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome.;Increase in the proportion of those with a positive tuberculin skin testing and no active tuberculosis who are started on treatment verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome.;Increase in the proportion of those who complete treatment verified through the contact registry book OBS: it is not possible to foresee in which proportion each of these steps will increase. The sample size was calculated based on a 20% increase of the primary outcome. | — |
Countries
Brazil
Contacts
Public ContactAnete Trajman
Universidade Federal do Rio de Janeiro
Outcome results
None listed