Schizophrenic,Exercise, Sedentary Behavior
Conditions
Interventions
After recruiting patients with Schizophrenia at the Centro de Atenção Psicossocial (CAPS) and the schizophrenia program at the Hospital de Clínicas de Porto Alegre (Prodesq), we performed the initial
Other
F01.145.632
Sponsors
Universidade Federal do Rio Grande do Sul
Hospital de clínicas de Porto Alegre
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients Diagnosis of schizophrenia according to DSM-5; Age between 18 and 65 years; Be under drug treatment; Not be involved in another physical activity program. Inclusion criteria for controls For the pairing of the controls, they were recruited by the same sex of the case, by age, 3 years upwards or downwards of the case, the same social class, and not to present a serious mental illness (dementia, depression, mania, generalized anxiety disorder or disorder obsessive-compulsive).
Exclusion criteria
Exclusion criteria: Exclusion criteria for patients Use alcohol or drugs in the last month; Systemic or neurological disease; Motor disability; Presence of suicide risk at the time of the intervention; Be pregnant; Don't accept to participate in the study. Exclusion criteria for controls They followed the same criteria as the cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect of aerobic exercise and postural exercise on motor functional capacity and posture in patients diagnosed with schizophrenia.;In the group of patients diagnosed with schizophrenia who underwent aerobic physical intervention, there was no improvement in motor functional capacity. In the postural intervention group, there was a greater difference in cases when compared to controls in the following domains of postural assessment, degree of posteroanterior misalignment of the head, degree of knee angle, degree of horizontal alignment of the tibial tuberosities, and degree of knee angle. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the severity of the disease using the BPRS scale; evaluate the behavior of markers of muscle injury and inflammation (lactate, troponin, C-reactive protein and creatinine kinase) after physical interventions; evaluate the degree of sedentary lifestyle by the Simpaq scale and evaluate the quality of life by the SF-36 scale;In the group of patients diagnosed with schizophrenia who underwent aerobic physical intervention, there was a decrease in weight, BMI (body mass index) and systolic and diastolic blood pressure. There was an increase in blood lactate markers, C-reactive protein, creatinine kinase, and there was no improvement in flexibility. On the SF-36 scale that measures quality of life, there was a positive improvement in functional capacity. On the Simpaq scale, there was an improvement in decreasing time, being sedentary. In the group of patients with schizophrenia who underwent postural intervention, there was an increase in blood lactate markers, C-reactive protein, creatinine kinase and troponin after the intervention. On the SF-36 scale, there was a significant improvement in the pain domain, which occurred after the intervention in the cases. | — |
Countries
Brazil
Contacts
Public ContactPaulo Belmonte-de-Abreu
Universidade Federal do Rio Grande do Sul
Outcome results
None listed