Alveolar bone loss
Conditions
Interventions
This is a randomized, controlled, three-arm, double-blind clinical study. Randomization will occur by randomly assigning participants, without distinction of sex or race, to one of three groups. There
D01.146.360.050
G16.762.150.150
D09.698.365.180.200
Sponsors
Universidade Estadual Vale do Acaraú
Universidade Federal do Ceará
Eligibility
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Spontaneous demand; screening between April and December 2025; signing of the free and informed consent form (FICF); adults between 20 and 40 years old; both sexes; all ethnicities; good systemic health; good oral hygiene; indication for premolar extraction due to trauma, endodontic complication or irreparable caries
Exclusion criteria
Exclusion criteria: Uncompensated diseases (hypertension, diabetes or coagulation disorder); pregnant and lactating women; smokers; irradiated; immunocompromised; users of antimicrobials or anti-inflammatories one month before the study; allergy to biomaterials or anesthetics; periapical lesions; need for ostectomy to complete the extraction; dehiscence or fenestrations observed during surgery; uncooperative patient during treatment or who does not return for reassessment (study withdrawal)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes will be the dimensional changes of the dental alveolus in width and height at baseline, immediately after surgery and after six months of alveolar repair. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes will include assessment of bone density, keratinized gingival changes, overall soft tissue healing, visual assessment of pain, and quality of life, after surgery and after six months of alveolar repair. | — |
Countries
Brazil
Contacts
Public ContactIgor Iuco Silva
Universidade Federal do Ceará
Outcome results
None listed