Stroke
Conditions
Interventions
The present study is a randomized, single-blind clinical trial. To meet the methodological criteria, up to 64 volunteers will be included. The interventions will take place at the School Health Unit o
205m) and their age (= 60 years old or >
60 years old). The experimental group will engage in a multimodal exercise training circuit with higher-intensity, with heart rates tagged at 70-84% of maximum heart rate. In contrast, the control gro
Sponsors
Universidade Federal de São Carlos
Irmandade Santa Casa de Misericórdia de São Carlos
Eligibility
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: Signed written informed consent; 40 - 80 years old; diagnosis of unilateral stroke between 6 up to 5 years before enrollment; ability to walk independently or with supervision and/or assistive devices; medical clearance for higher intensity exercise; preserved cognition, characterized by the ability to follow simple commands and to identify themselves in space and time; participants must be physically inactive, defined as <7,500 steps per day; participants must be willing and able to refrain from participation in any additional structured exercise or physical activity programs during the trial period
Exclusion criteria
Exclusion criteria: Cardiac surgery and/or acute myocardial infarction within one month; use a pacemaker; have obstructive or restrictive pulmonary disease; participants who withdraw their consent or experience severe symptoms during assessments or intervention; other neurological diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We expect to increase the daily steps (measured by ActiviPAL4TM micro). Assessments are made 15 days before the treatment, one week after the treatment, and six weeks after reassessment;We expect to improve the endothelium function (measured by Flow Mediated Dilatation brachial artery). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to improve cardiac function (left ventricular ejection). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment | — |
Secondary
| Measure | Time frame |
|---|---|
| We expect to improve the self-perceived assistance level, performance quality, and confidence (Lower Extremity Motor Activity Log). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to increase the walk endurance (6-minute walk test);We expect to improve the cardiac function (Transthoracic echocardiogram);We expect to reduce the carotid intima-media thickness (Carotid ultrasound);We expect to increase the heart rate variability (assessed by Polar and active postural change);We expect to improve the laboratory tests (assessed by collecting a blood sample);We expect to reduce the duration of Physical Inactivity (ActiviPAL4TM micro). Assessments are made 15 days before the treatment, one week after the treatment, and six weeks after reassessment ;We expect to reduce the sedentary behavior (ActiviPAL4TM micro). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to increase physical activity level (ActiviPAL4TM micro). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to improve the marching cadence (ActiviPAL4TM micro). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to improve the quality of Life (Stroke Specific Quality of Life Questionnaire). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to reduce sensorimotor impairment (Fugl-Meyer). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to improve the functional balance (Dynamic Gait Index and Timed Up and Go). Assessments are made 15 days prior to the treatment, one week after the treatment, and 6 weeks after reassessment;We expect to increase walking speed (Ten Meter Walk Test | — |
Countries
BR
Contacts
Public ContactThiago de Russo
Universidade Federal de São Carlos
Outcome results
None listed