Arterial Pressure Menopause
Conditions
Interventions
This is a randomized, double-blind, crossover, placebo-controlled clinical trial. Participants who meet the eligibility criteria will be probabilistically allocated to one or the other intervention gr
Sponsors
Fundaçao Universidade de Pernambuco
Fundaçao Universidade de Pernambuco
Eligibility
Sex/Gender
Female
Age
38 Years to 60 Years
Inclusion criteria
Inclusion criteria: Women aged 40 to 60 years with body index mass of 18.5 to 34.9 kilograms per square meter and low density lipoprotein high or equal to 130 milligrams per deciliter will participate in the study; All participants must be postmenopausal at the start of the intervention; Age at menopause will be categorized as under 45 years early menopause 45 to 49 years relatively early menopause 50 to 51 years reference or 51 years or older relatively late menopause; They must have had no menses in the last year; Able to comply with the study protocols; They must not have any pathologies that could affect their nutritional status; During participation in this clinical trial all women will receive special attention to ensure their well-being comfort and safety; The study was ethically designed to minimize any physical risks associated with the data collection steps
Exclusion criteria
Exclusion criteria: Self-reported use of anticoagulant agents including nonsteroidal anti-inflammatory drugs oral cortisone or other immunosuppressive agents; Presence of neoplasia or immunological disease; Restricted or reduced physical activity due to chronic health conditions; Blood pressure high or equal to 140/90 millimeters of mercury; Kidney or liver disease; Heart disease including cardiovascular events or stroke; Cancer diagnosis in the last five years; Inability to comply with study requirements and procedures; Inability to perform treadmill test due to limitations such as orthopedic problems or moderate to severe aortic stenosis; History of myocardial infarction in the last three months or angina under treatment; Inability to perform handgrip test due to limitations such as pain or deformity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate whether oral resveratrol supplementation attenuates cardiovascular recovery after submaximal aerobic exercise on a treadmill compared with placebo through the analysis of cardiovascular parameters measured before and after the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the effect of oral resveratrol supplementation on resting blood pressure and heart rate measured before and after the intervention through standardized cardiovascular monitoring | — |
Countries
BR
Contacts
Public ContactJuliana Alves
Fundaçao Universidade de Pernambuco
Outcome results
None listed