Skip to content

Pain control in breast surgery: analgesia, opioide consumption and inflamatory response evaluation

Pain control in breast surgery: analgesia, opioide consumption and inflamatory response evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2fjmhz
Enrollment
Unknown
Registered
2017-10-31
Start date
2015-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with breast neoplasia CID10 D-48 and deCS C04.588.180

Interventions

Thus, the serratus anterior muscle plane (SAM) block associated with pectoral nerve block type I (PEC I) may be a safe and effective alternative for the intraoperative of breast surgery, since there i
post-operative pain and release of plasma inflammatory cytokines. It is a clinical prospective, randomized and controlled study. 50 individuals will be randomly divided into two groups. A group of pat
Procedure/surgery

Sponsors

Hospital Sírio-Libanês
Lead Sponsor
Hospital Sírio-Libanês
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients ASA I and II submitted to radical mastectomy with breast reconstruction

Exclusion criteria

Exclusion criteria: Patients with allergy to local anesthesic, patients with chronic pain previous to surgery

Design outcomes

Primary

MeasureTime frame
The postoperative pain will be assessed using the Visual Analogue Scale pain in the recovery room and 24 hours after surgery. It is expected a reduction in 1.5 points in this scale considering patients that belong to the block group.

Secondary

MeasureTime frame
Reduction in the inflamatory profile (seric cytokines), measured using Elisa method, from blood samples collected before and 24h after the surgery, considering variation of at least 5%.

Countries

Brazil

Contacts

Public ContactMarcio Matsumoto

Hospital Sírio-Libanês

marciomatsumoto46@hotmail.com+55(11)33944779

Outcome results

None listed

Source: REBEC (via WHO ICTRP)