Inflammation, Gene Expression, Hormones, protein and Enzymes
Conditions
Interventions
Sponsors
Faculdade de Medicina de Botucatu
Faculdade de Medicina de Botucatu
Eligibility
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Healthy individual;both sexes; aged between 18 and 50 years; who do not present other disease unless the operative condition; undergoing otorhinolaryngologic elective surgery; lasting at least 90 minutes
Exclusion criteria
Exclusion criteria: Smoking; using illicit drugs and alcohol; users of daily vitamin supplements and / or antipyretics; analgesics; antibiotics; anti-inflammatory; among others; the occupationally exposed to paints; fuel; pesticides and hospital environments; those who received radiation ionizing or MRI done in less than 30 days; those who have already undergone chemotherapy or radiotherapy; patients with diseases such as asthma, hypertension; diabetes; cancer; infectious or inflammatory processes; and those who are not referred for surgery of ENT and ophthalmology clinic.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the comparison of anesthesia maintained with desflurane or desflurane + 60% of N2O showed similarity of inflammatory and neuro-endocrine markers evaluated during and after septoplasty surgery; in addition, there was a significant increase in intraoperative prolactin and IL-6 inflammatory mediators and in the postoperative period in both groups | — |
Secondary
| Measure | Time frame |
|---|---|
| there were no secondary outcomes | — |
Countries
Brazil
Contacts
Public ContactNayara Micarelli de Arruda
Faculdade de Medicina de Botucatu
Outcome results
None listed