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The Safety and Efficacy of Target-Controlled Infusion versus Intermittent Bolus of propofol for Sedation on Colonoscopy: A Controlled Randomized Study

The Safety and Efficacy of Target-Controlled Infusion versus Intermittent Bolus of propofol for Sedation on Colonoscopy: A Controlled Randomized Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2dxshp
Enrollment
Unknown
Registered
2017-10-05
Start date
2017-08-16
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon polyps

Interventions

Experimental Group : 25 patients undergoing colonoscopy under sedation with target control infusion of Propofol and manual bolus of Fentanyl 1 ug/kg IV. The target of Propofol was titrated until loss
Device

Sponsors

Associação Matogrossense de Combate ao Câncer
Lead Sponsor
Hospital de Cãncer de Mato Grosso
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with Physical Status I and II according American Society of Anesthesiologists ( ASA ); undergoing colonoscopy; aged 18 to 65 years; both gender and Body Mass Index ( BMI ) less than 30; accept to sign the Informed Consent

Exclusion criteria

Exclusion criteria: Patients with a history of allergy to any of the medicines; Body Mass Index greater than 30; refusal to sign the informed conset

Design outcomes

Primary

MeasureTime frame
Reduction of at least 25% of the number of interventions in the target-controlled infusion group. The following interventions were considered: Propofol dose adjustment by agitation and airway rescue maneuvers if oxygen saturation less than 92% that was verified by pulse oximete during the colonoscopy.

Secondary

MeasureTime frame
Faster awakening in the target-controlled infusion group verified by the time between the end of the colonoscopy and the patient exhibiting OAAS score ( Observer Assessment of Alertness and Sedation ) greater than or equal to 3

Countries

Brazil

Contacts

Public ContactIgor Cuiabano

Associação Matogrossense de Combate ao Câncer

igorserorcuiabano@gmail.com+556536487575

Outcome results

None listed

Source: REBEC (via WHO ICTRP)