Temporomandibular disorder
Conditions
Interventions
Treated Group (group T): 20 females volunteers received treatment with counseling and injection of 50U of botulinum toxin in the masseter muscles and 20U in the temporal muscles in a single session wi
Drug
Device
Radiation
Sponsors
Faculdade de Odontologia de Piracicaba, Universidade estadual de Campinas
Faculdade de Odontologia de Piracicaba, Universidade estadual de Campinas
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Female volunteers; aged 18-45 years; with muscular TMD; with pain for more than 3 months; using contraception; with all teeth; class I of Angle; having stable occlusion.
Exclusion criteria
Exclusion criteria: Volunteers with trauma in the face and TMJ; with bruxism; wearing dentures; on orthodontic treatment; using anti-inflammatory medication, analgesic and / or muscle relaxant; with coagulopathy; with neuralgia; with arthritis; osteoarthritis; diabetes; neurological disorders; primary headache; fibromialgy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain reduction verified through the methods of Visual Analog Scale (VAS) and Pain to Pressure Threshold (LDP), from the evidence of a decrease of at least 2 points in VAS and 5% in LDP before intervention and 7,14,21,28,90 e 180 days after intervention.;Pain reduction in a period of six months, verified through the methods of Visual Analog Scale (VAS) and Pain to Pressure Threshold (LDP), from the evidence of a decrease of at least 2 points in VAS and 5% in LDP in pre and post intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in chewing efficiency over a six-month period, verified by the sieve fractionation method, based on evidence of at least 15% decrease in pre and post-intervention measurements.;Decrease in mandibular bone volume over a period of six months, verified by the conical beam computerized tomography method, based on evidence of a decrease of at least 5% in pre and post-intervention measurements.;Decrease in muscle thickness of the masseter and temporal muscles over a period of six months, verified by the ultrasound method, with evidence of a decrease of at least 5% in pre and post-intervention measurements.;Decrease in the electrical activity of the masseter and temporal muscles over a period of six months, verified by the surface electromyography method, from the evidence of a decrease of at least 10% in the pre and post intervention measurements. | — |
Countries
Brazil
Contacts
Public ContactGiancarlo De la Torre
Faculdade de Odontologia de Piracicaba, Universidade estadual de Campinas
Outcome results
None listed