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Effects of Brain Stimulation combined with Neural Mobilization in people with sciatica

Effects of Transcranial Direct Current Stimulation on pain, disability and quality of life in individuals with chronic sciatica: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-2d3jj9t
Enrollment
Unknown
Registered
2023-06-04
Start date
2023-03-28
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sciatic Neuropathy

Interventions

E02.331
This is a two-arm, blinded, randomized controlled clinical trial. Experimental group: 19 men and women between 18 and 64 years old with complaints of pain radiating to the leg for more than three mont
then three Neural Mobilization maneuvers will be performed, with 3 series of 30 oscillations for each maneuver. Control group: 19 men and women between 18 and 64 years old complaining of pain radiatin
then three Neural Mobilization maneuvers will be performed, with 3 series of 30 oscillations for each maneuver. The allocation of the participants will be done randomly through opaque sealed envelopes
E02.331.750
E02.190.599

Sponsors

Universidade Federal do Rio Grande do Norte
Lead Sponsor
Universidade Federal do Rio Grande do Norte
Collaborator

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Men and women between 18 and 64 years. Clinical diagnosis of low back-related leg pain for at least three months. Radiating pain to at least one lower limb in the last two weeks. Presence of two or more of the following clinical criteria; positive neural tension test (SLRT); neurological deficit; pain below the knee; pain more present in the leg than in the lumbar; and subjective sensory symptoms. Not being under physiotherapeutic treatment for low back-related leg pain for at least 60 days

Exclusion criteria

Exclusion criteria: To present any contraindication for tDCS brain stimulation; Douleur Neuropathique Questionnaire score under 4 points; Pain Numeric Rating Scale score under 3 points; Presence of Red Flags for critical spinal pathology; Have been submitted to some type of infiltration in the spine in the last six months; History of abdominal, lumbar or lower limb surgery in the last year; Inability to respond to the study's assessment instruments

Design outcomes

Primary

MeasureTime frame
A reduction in Pain Intensity assessed by the Numerical Pain Scale is expected to be found, it will be considered a change in the endpoint when the result after the intervention is a reduction equal to or greater than two points on the scale.

Secondary

MeasureTime frame
Neuropathic Symptoms evaluated by the Douler Neuropathic Questionnaire (DN4) are expected to be reduced by reducing the score to less than 4 points; as will Pain Detect Questionnaire (PDQ) scores below 12; in these situations the pain complaint is no longer classified as Neuropathic Pain.;A reduction in Disability as assessed by the Roland Morris Disability Questionnaire is expected, detected through a 4/24 point reduction in the post intervention assessment.

Countries

Brazil

Contacts

Public ContactAryostennes Ferreira

Universidade Federal do Rio Grande do Norte

aryostennes.ferreira.066@ufrn.edu.br+5583999326940

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 1, 2026