Association of genetic differences in the inflammation of patients with traumatized teeth

Conditions

Polymorphism, Genetic

Related papers

No related papers found yet.

Interventions

50 patients who had their teeth replanted and treated endodontically were selected. The radiographic evaluation was performed with periapical radiographs taken next to replantation and after 1 year

Other

C07.793.901

Eligibility

Age

7 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients of both genders. Teeth avulsed and replanted

Exclusion criteria

Exclusion criteria: Immunocompromised patients. Patients taking continuous medication.

Design outcomes

Primary

Measure	Time frame
Statistical analyses were performed by 21.0 SPSS version. The non-parametric Mann-Whitney test was used to analyze quantitative variables. Categorical variables were analyzed by chi-square test or Fisher's exact test. P values lower than 0.05 were considered significant. For the multivariate analysis, the binary logistic regression model was fitted to analyze the genotype frequencies, including the variables with significance set at p lower than 0.20.The univariate analysis was used to associate age, extra-alveolar time and the storage medium with root resorption. After multivariate analysis, the extra-alveolar time longer than one hour and the G allele of rs2069843 of the IL6 gene were significantly associated with external root resorption.	—

Measure

Time frame

Statistical analyses were performed by 21.0 SPSS version. The non-parametric Mann-Whitney test was used to analyze quantitative variables. Categorical variables were analyzed by chi-square test or Fisher's exact test. P values lower than 0.05 were considered significant. For the multivariate analysis, the binary logistic regression model was fitted to analyze the genotype frequencies, including the variables with significance set at p lower than 0.20.The univariate analysis was used to associate age, extra-alveolar time and the storage medium with root resorption. After multivariate analysis, the extra-alveolar time longer than one hour and the G allele of rs2069843 of the IL6 gene were significantly associated with external root resorption.

—

Secondary

Measure	Time frame
Statistical analyses were performed by 21.0 SPSS version. The non-parametric Mann-Whitney test was used to analyze quantitative variables. Categorical variables were analyzed by chi-square test or Fisher's exact test. P values lower than 0.05 were considered significant. For the multivariate analysis, the binary logistic regression model was fitted to analyze the genotype frequencies, including the variables with significance set at p lower than 0.20.The univariate analysis was used to associate age, extra-alveolar time and the storage medium with root resorption. After multivariate analysis, the extra-alveolar time longer than one hour and the G allele of rs2069843 of the IL6 gene were significantly associated with external root resorption.	—

Measure

Time frame

Statistical analyses were performed by 21.0 SPSS version. The non-parametric Mann-Whitney test was used to analyze quantitative variables. Categorical variables were analyzed by chi-square test or Fisher's exact test. P values lower than 0.05 were considered significant. For the multivariate analysis, the binary logistic regression model was fitted to analyze the genotype frequencies, including the variables with significance set at p lower than 0.20.The univariate analysis was used to associate age, extra-alveolar time and the storage medium with root resorption. After multivariate analysis, the extra-alveolar time longer than one hour and the G allele of rs2069843 of the IL6 gene were significantly associated with external root resorption.

—

Countries

Brazil

Contacts

Public ContactLiliane Roskamp

Pontifícia Universidade Católica do Paraná

lroskamp@gmail.com+55-041-999760245

Outcome results

None listed