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Association of Infection with Parenteral Nutrition

Infection associated with Parenteral Nutrition: Retrospective cohort study in tertiary hospital and systematic review with meta-analysis on the association of Parenteral Nutrition with infections and mortality

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-2brcxq
Enrollment
Unknown
Registered
2018-09-12
Start date
2016-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Interventions

250 patients received parenteral nutrition two in one (2: 1), combining glucose and amino acid, being separated from the intravenous lipid emulsion. This therapy was performed for as long as the docto
Other
E02.421.505

Sponsors

Programa Pós-Graduação em Endocrinologia da Universidade Federal do Rio Grande do Sul
Lead Sponsor
Programa Pós-Graduação em Endocrinologia da Universidade Federal do Rio Grande do Sul
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients submitted to NP admitted to the Hospital de Clínicas de Porto Alegre (HCPA).

Exclusion criteria

Exclusion criteria: Central peripheral insertion catheter. Central catheter for long stay. Sustained parenteral nutrition less than 72 h after onset.

Design outcomes

Primary

MeasureTime frame
Rate of positive blood cultures, verified by the analysis of the results of the hospital laboratory, in patients with no other outbreak of infection detected clinically, suggesting infection related to the use of central venous catheter. Blood cultures were processed in automated system Bactec 9120 (Becton Dickinson). Positive samples were stained by gram and seeded in selective media (MacConkey agar, mannitol agar, blood agar). The result will be presented in percentage of cases of infection on the number of total cases of patients under parenteral nutrition.

Secondary

MeasureTime frame
Death rate at the current hospitalization, verified by hospital discharge or death register of the present hospitalization, by electronic medical record, in all patients submitted to parenteral nutrition. The result will be presented in percentage: number of deaths on the number of patients who were submitted to parenteral nutrition in the period.

Countries

Brazil

Contacts

Public ContactPedro Comerlato

Programa Pós-Graduação em Endocrinologia da Universidade Federal do Rio Grande do Sul

pedrocomerlato@hotmail.com+55-051-999545988

Outcome results

None listed

Source: REBEC (via WHO ICTRP)